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SYD5115 (SYD-5115, SYD 5115)

  Cat. No.:  DC73511  
Chemical Structure
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Field of application
SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively.
Cas No.:
Chemical Name: SYD5115 (SYD-5115, SYD 5115)
SMILES: O=C(O[C@H](C(C)(C)C)C)NC1=NC=C(N(C(C)=O)C2(C)C)C(C32CCC(F)(F)CC3)=N1
Formula: C22H32F2N4O3
M.Wt: 438.52
MSDS
Cat. No. Product name Field of application
DC73510 Org 274179-0 Org 274179-0 is a highly potent, allosteric antagonist of the thyroid-stimulating hormone receptor (TSH receptor), inhibits bTSH-, hTSH- and M22-mediated CRE-luciferase transactivation in the CHO cell line.
DC40415 TSHR antagonist S37b TSHR antagonist S37b is an enantiomer of TSHR antagonist S37a, shows only a minor effect for TSHR inhibition. TSHR antagonist S37b can be used for the research of thyroid function.
DC73511 SYD5115 (SYD-5115, SYD 5115) SYD5115 (SYD-5115) is a potent, selective and orally bioavailable thyrotropin receptor (TSH-R) antagonist with IC50 of 48 and 62 nM for rTSHR and hTSHR, respectively.
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