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MK-886

Cat. No.: DC73518

Chemical Structure

118414-82-7

For research use only. We do not sell to patients.

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Field of application

MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 30 nM.

MSDS

Cat. No.	Product name	Field of application
DC73518	MK-886	MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 30 nM.
DC70142	GSK2190915 sodium	A potent, selective FLAP inhibitor with binding IC50 of 2.6 nM; inhibits LTB4 synthesis following ionophore challenge in human whole blood with IC50 of 76 nM (5 h incubation); shows good selectivity over CYP3A4, 2C9, and 2D6; exhibits excellent preclinical toxicology, pharmacokinetics and oral bioactivity.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.