Cat. No. | Product name | CAS No. |
DC9586 |
Telatinib
Featured
Telatinib(Bay 57-9352) is a potent inhibitor of VEGFR2/3, c-Kit and PDGFRα with IC50 of 6 nM/4 nM, 1 nM and 15 nM, respectively. |
332012-40-5 |
DC10150 |
Tenalisib
Tenalisib (RP6530) is a novel, potent, and selective PI3Kδ and PI3Kγ inhibitor with IC50 values of 25 and 33 nM, respectively. |
1639417-53-0 |
DC10386 |
Tenapanor
Featured
Tenapanor is an inhibitor of the Na+/H+ exchanger NHE3 with IC50 values of 5 and 10 nM against human and Rat NHE3, respectively. |
1234423-95-0 |
DCAPI1383 |
Terbinafine (Lamisil, Terbinex)
Terbinafine (Lamisil, Terbinex) |
91161-71-6 |
DCAPI1344 |
Terbinafine HCl
Featured
Terbinafine also known under the trade name Lamisil. It is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue. It is on the WHO Model List of Essential Medicines, the most important medications needed in a basic health system. |
78628-80-5 |
DC9609 |
Terutroban
Featured
Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist. |
165538-40-9 |
DC7516 |
TG100-115
Featured
TG100115 is a PI3Kγ/δ inhibitor with IC50 of 83 nM/235 nM, with little effect on PI3Kα/β. Phase 1/2. |
677297-51-7 |
DC7317 |
TG101209
Featured
TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, ~30-fold selective for JAK2 than JAK3, sensitive to JAK2V617F and MPLW515L/K mutations; TG101209 inhibit BRD4 activity with IC50 of 130 nM. |
936091-14-4 |
DC7318 |
TG101348(Fedratinib)
Featured
TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM, 35- and 334-fold more selective for JAK2 versus JAK1 and JAK3, TG-101348 also inhibit BRD4 with IC50 of 340 nM. |
936091-26-8 |
DC8652 |
TGR-1202 hydrochloride(Umbralisib)
TGR-1202 hydrochloride is an orally available, next generation PI3Kdelta inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 and 24.3 nM respectively. |
1532533-78-0 |
DC8653 |
TGR-1202(Umbralisib)
Featured
TGR-1202 is an orally available, next generation PI3Kdelta inhibitor, inhibits PI3Kδ activity in enzyme and cell based assays with IC50 and EC50 values of 22.2 and 24.3 nM respectively. |
1532533-67-7 |
DC7689 |
Evofosfamide(TH-302)
Featured
TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumors with IC50 of 19 nM, demonstrates 270-fold enhanced cytotoxicity under hypoxia versus their potency under aerobic conditions, stable to cytochrome P450 metabolism. |
918633-87-1 |
DC11492 |
GMX-1777 chloride
The water-soluble prodrug of GMX-1778 (CHS-828), which is a potent and specific inhibitor of the NAD(+) biosynthesis enzyme NAMPT with IC50 of <20 nM. |
432037-57-5 |
DC5192 |
TIC10 isomer
TIC10 isomer(ONC201 isomer) is an isomer of TIC10; TIC10 is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier. |
41276-02-2 |
DC1101 |
Ticagrelor (Brilinta,AZD6140)
Featured
Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist, also inhibits CYP2C9 and 4-hydroxylation with IC50 of 10.5 μM and 8.2 μM respectively. |
274693-27-5 |
DC10478 |
Tinostamustine(EDO-S101)
Featured
Tinostamustine is the first representative of the A-DAC principle, a new approach in chemotherapy that uses fusion technology to combine an alkylating agent with a pan-histone deacetylase inhibitor (HDAC) to simultaneously damage DNA and block damage repa |
1236199-60-2 |
DCAPI1449 |
Tiotropium Bromide
Featured
Tiotropium Bromide is a muscarinic acetylcholine receptor (mAChR M) antagonist that blocks the binding of the acetylcholine ligand and subsequent opening of the ligand-gated ion channel. This stops signaling between neurons and leads to muscle relaxation. |
136310-93-5 |
DC9701 |
Tipifarnib
Featured
Tipifarnib (IND 58359; R115777) is a potent and specific farnesyltransferase inhibitor with an IC50 of 0.6 nM. |
192185-72-1 |
DC9489 |
Tirofiban (hydrochloride monohydrate)
Featured
Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist |
150915-40-5 |
DC7327 |
Tirofiban(L700462;MK383)
Featured
Tirofiban(L700462;MK383) is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist. |
144494-65-5 |
DC7065 |
Tivantinib (ARQ 197)
Featured
Tivantinib (ARQ 197) is the first non-ATP-competitive c-Met inhibitor with Ki of 0.355 μM, little activity to Ron, and no inhibition to EGFR, InsR, PDGFRα or FGFR1/4. |
905854-02-6 |
DC5078 |
Tivozanib(AV-951)
Featured
Tivozanib (AV-951, KRN-951) is a potent and selective VEGFR inhibitor for VEGFR1/2/3 with IC50 of 0.21 nM/0.16 nM/0.24 nM, and also inhibits PDGFR and c-Kit, low activity observed against FGFR-1, Flt3, c-Met EGFR and IGF-1R. |
475108-18-0 |