Cat. No. | Product name | CAS No. |
DC10523 |
TAK-659 HCl
Featured
TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM. |
1952251-28-3 |
DC7304 |
TAK 715
TAK-715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM, 28-fold more selective for p38α over p38β, no inhibition to p38γ/δ, JNK1, ERK1, IKKβ, MEKK1 or TAK1. |
303162-79-0 |
DC7308 |
TAK-733
Featured
TAK-733 is a potent and selective MEK allosteric site inhibitor for MEK1 with IC50 of 3.2 nM, inactive to Abl1, AKT3, c-RAF, CamK1, CDK2, c-Met, etc. |
1035555-63-5 |
DC11397 |
TAK-779
Featured
TAK-779 is a potent and selective nonpeptide antagonist of CCR5 and CXCR3, with a Ki of 1.1 nM for CCR5, and effectively and selectively inhibits R5 HIV-1, with EC50 and EC90 of 1.2 nM and 5.7 nM, respectively, in MAGI-CCR5 cells. |
229005-80-5 |
DC5073 |
TAK-875(Fasiglifam)
Featured
TAK-875 is a potent, selective and orally bioavailable GPR40 agonist with EC50 of 0.072 μM. |
1000413-72-8 |
DC11370 |
TAK-901
TAK-901 is a non-selective Aurora kinase inhibitor (IC50s = 3.1, 10, and 4.2 nM for Aurora A, B, and C, respectively). |
934541-31-8 |
DC8739 |
Talabostat mesylate
Talabostat mesilate(PT-100; Val-boroPro) is an orally active, specific inhibitor of dipeptidyl peptidases(IC50=1 nM for DPP4), including tumor-associated fibroblast activation protein. |
150080-09-4 |
DC9180 |
Tamoxifen Citrate
Featured
Tamoxifen(ICI-46474) is an antagonist of the estrogen receptor in breast tissue via its active metabolite, hydroxytamoxifen,showed potent activity against COVID-19(SARS-COV-2) with EC50 MERS-COV(10.117), SARS-COV(11.696). |
54965-24-1 |
DC7894 |
Tandutinib(MLN518)
Tandutinib (MLN518, CT53518) is a potent FLT3 antagonist with IC50 of 0.22 μM, also inhibits PDGFR and c-Kit, 15 to 20-fold higher potency for FLT3 versus CSF-1R and >100-fold selectivity for the same target versus FGFR, EGFR and KDR. Phase 2. |
387867-13-2 |
DC7769 |
Tanomastat
Tanomastat is an angiogenesis and Matrix Metalloproteinase inhibitor |
179545-77-8 |
DC4158 |
Tranabant (MK-0364)
Taranabant is a highly selective cannabinoid-1 (CB1) receptor inverse agonist. |
701977-09-5 |
DC1102 |
Tariquidar (XR9576)
Featured
Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with Kd of 5.1 nM. |
206873-63-4 |
DC7312 |
Tasisulam(LY573636)
Featured
Tasisulam sodium is The sodium salt of an acyl-sulfonamide with potential antineoplastic activity. |
519055-62-0 |
DC7733 |
Tasquinimod(ABR-215050)
Featured
Tasquinimod is an orally active antiangiogenic agent by allosterically inhibiting HDAC4 signalling. |
254964-60-8 |
DC7940 |
TBA-354
TBA-354 is a potent anti-tuberculosis compound; maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. |
1257426-19-9 |
DC10390 |
TD139
Featured
TD139 is a novel high-affinity inhibitor of the galectin-3 carbohydrate binding domain with a Kd of 14 nM. |
1450824-22-2 |
DC8813 |
TD-4208
Featured
TD-4208 is a potent and selective inhaled muscarinic antagonist with functional lung selectivity and long duration of action in preclinical models of bronchoconstriction. |
864750-70-9 |
DC2067 |
TDZD-8
Featured
TDZD-8 is a non-ATP competitive GSK-3β inhibitor with IC50 of 2 μM. |
327036-89-5 |
DC11026 |
Tecovirimat
Featured
Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, c |
869572-92-9 |
DC8962 |
Tegafur
Featured
Tegafur (also known as Ftorafur) is a chemotherapeutic 5-FU prodrug used in the treatment of cancers; is a component of tegafur-uracil. |
17902-23-7 |
DC7515 |
Teglicar
Featured
Teglicar, in vitro and in animal models, reduces gluconeogenesis and improves glucose homeostasis, refreshing the interest in selective and reversible L-CPT1 inhibition as a potential antihyperglycemic approach. |
250694-07-6 |
DC1008 |
Telaprevir (VX-950)
Featured
Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor with IC50 of 0.35 μM. |
402957-28-2 |