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Therapeutic Antibodies

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Cat. No. Product Name Field of Application Chemical Structure
A472 Atinumab (NG-101) Featured
A473 LK-1 Featured
A474 CDX-0158 Featured
A475 LOP628 Featured
A476 Wuhan U. patent anti-Nav1.9 Featured
A477 Duke anti-NAv1.7 Featured
A478 Pepinemab Featured Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.
A479 Sanofi patent anti-PAI-1 Featured
A480 Abbv-011 Featured
A481 Pritoxaximab Featured Pritoxaximab is an IgG1κ antibody targeting shiga toxin type 1.
A482 Setoxaximab Featured Setoxaximab is an IgG1-κ humanized chimeric antibody targeting shiga toxin type 1.
A483 MVT-5873 Featured
A484 AB-25E9 Featured
A485 NC-318 (5G-12) Featured
A486 Medimmune patent anti-Siglec-15 Featured
A487 Epratuzumab Featured Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases.
A488 Pinatuzumab Featured Pinatuzumab is a CD22 monoclonal antibody. Pinatuzumab targets the cell-surface antigen CD22. Pinatuzumab can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including non-Hodgkin lymphoma (NHL).
A489 Inotuzumab-CLM Featured
A490 Anti-Siglec-2/CD22 Antibody (NCI m971) Featured
A491 Anti-Siglec-2/CD22 Antibody (NCI m972) Featured
A492 IMGN779 Featured
A493 Vadastuximab Featured Vadastuximab is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine.
A494 Gemtuzumab Featured Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia.
A495 Refanezumab Featured Refanezumab (GSK249320) is an IgG1-type humanized monoclonal antibody directed against myelin-associated glycoprotein (MAG). Refanezumab binds to MAG and blocks MAG-mediated inhibition of axonal regeneration. Refanezumab can cross the blood-brain barrier (BBB) in animal stroke models. Refanezumab has the potential for the enhancement of recovery of function poststroke.
A496 Lirentelimab Featured Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis.
A497 BI 765063 Featured
A498 Hospital for Sick Children patent anti-SIRPA Featured
A499 KWAR 23 Featured KWAR23 is an anti-human SIRPα antibody. KWAR23 binds human SIRPα with high affinity and disrupts its binding to CD47. KWAR23 shows antitumor activity in combination with tumor-opsonizing antibodies and can be used in cancer immunotherapy research.
A500 SGN-CD352A Featured
A501 Azintuxizumab Featured Azintuxizumab is an anti-SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin.

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