A472 |
Atinumab (NG-101)
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A473 |
LK-1
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A474 |
CDX-0158
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A475 |
LOP628
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A476 |
Wuhan U. patent anti-Nav1.9
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A477 |
Duke anti-NAv1.7
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A478 |
Pepinemab
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Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D. |
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A479 |
Sanofi patent anti-PAI-1
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A480 |
Abbv-011
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A481 |
Pritoxaximab
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Pritoxaximab is an IgG1κ antibody targeting shiga toxin type 1. |
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A482 |
Setoxaximab
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Setoxaximab is an IgG1-κ humanized chimeric antibody targeting shiga toxin type 1. |
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A483 |
MVT-5873
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A484 |
AB-25E9
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A485 |
NC-318 (5G-12)
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A486 |
Medimmune patent anti-Siglec-15
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A487 |
Epratuzumab
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Epratuzumab (Antibody hLL 2) is an anti-CD22 IgG1 monoclonal antibody. Epratuzumab is also a tumor-imaging agent and an immunomodulatory agent. Epratuzumab can induce CD22 phosphorylation. Epratuzumab has been used to research non-Hodgkin’s lymphomas (NHL) and certain autoimmune diseases. |
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A488 |
Pinatuzumab
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Pinatuzumab is a CD22 monoclonal antibody. Pinatuzumab targets the cell-surface antigen CD22. Pinatuzumab can be used for synthesis of antibody agent conjugates (ADCs) to research several diseases including non-Hodgkin lymphoma (NHL). |
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A489 |
Inotuzumab-CLM
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A490 |
Anti-Siglec-2/CD22 Antibody (NCI m971)
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A491 |
Anti-Siglec-2/CD22 Antibody (NCI m972)
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A492 |
IMGN779
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A493 |
Vadastuximab
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Vadastuximab is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine. |
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A494 |
Gemtuzumab
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Gemtuzumab is a monoclonal IgG4-κ antibody targeting CD33 antigen, which present on leukemic myeloblasts of acute myeloid leukemia (AML). Gemtuzumab can be used for synthesis of antibody-drug conjugate (ADC), Gemtuzumab ozogamicin (HY-109539). Gemtuzumab ozogamicin consists of a cytotoxic derivative of Calicheamicin (a cytotoxic antibiotic), and a monoclonal antibody. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia. |
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A495 |
Refanezumab
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Refanezumab (GSK249320) is an IgG1-type humanized monoclonal antibody directed against myelin-associated glycoprotein (MAG). Refanezumab binds to MAG and blocks MAG-mediated inhibition of axonal regeneration. Refanezumab can cross the blood-brain barrier (BBB) in animal stroke models. Refanezumab has the potential for the enhancement of recovery of function poststroke. |
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A496 |
Lirentelimab
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Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis. |
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A497 |
BI 765063
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A498 |
Hospital for Sick Children patent anti-SIRPA
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A499 |
KWAR 23
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KWAR23 is an anti-human SIRPα antibody. KWAR23 binds human SIRPα with high affinity and disrupts its binding to CD47. KWAR23 shows antitumor activity in combination with tumor-opsonizing antibodies and can be used in cancer immunotherapy research. |
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A500 |
SGN-CD352A
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A501 |
Azintuxizumab
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Azintuxizumab is an anti-SLAMF7 human IgG4κ monoclonal antibody. Azintuxizumab can be used in the synthesis of antibody-drug conjugate (ADC), Azintuxizumab vedotin. |
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