| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC46965 | Tri-GalNAc-COOH Featured | tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research. |
|
| DC47877 | tri-GalNAc-COOH (acetylation) Featured | tri-GalNAc-COOH acetylation is the acetylated and modified form of tri-GalNAc-COOH. tri-GalNAc-COOH acetylation can be used for the synthesis of LYTAC. |
|
| DC71975 | TriGalNAc CBz Featured | TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies. |
|
| DC72269 | Tri-GalNAc(OAc)3 TFA Featured | Tri-GalNAc(OAc)3 TFA is a tri-GalNAc ligand that can be used for the synthesis of GalNAc-LYTAC. GalNAc-LYTAC engages the asialoglycoprotein receptor for targeted protein degradation. tri-GalNAc: triantenerrary N-acetylgalactosamine; LYTAC: lysosome-targeting chimera. |
|
| DC72546 | Tri-GalNAc-NHS ester Featured | Tri-GalNAc-NHS ester is a LYsosome TArgeting Chimera (LYTAC) and a ligand of asialoglycoprotein receptor (ASGPR). ASGPR is a lysosomal targeting receptor specifically expressed on liver cells, for the degradation of extracellular proteins including membrane proteins. Tri-GalNAc-NHS ester can be used as a protein degrader and it can be used for the research of LYTAC. |
|
| DC65560 | GalNAc-L96 free base Featured | GalNAc-L96 free base, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs. |
|
| DC65559 | GalNAc-L96 Phosphoramidite Featured |
|
|
| DC65561 | GalNac-L96 analog Featured | GalNAc-L96 analog is an intermediate in the synthesis of the asialoglycoprotein receptor (ASGPR) ligand GalNAc-L96. |
|
| DC65562 | GalNAc-NAG-25 Phosphoramidite Featured |
|
|
| DC65563 | GalNAc-L96-CPG Featured |
|
|
| DC65564 | GalNAc-L96-PS Featured |
|
|
| DC65565 | GalNac-L96 Featured | GalNac-L96, the G-rich oligonucleotides carrying the longer GalNAc linker that can be used for delivery of nucleic acid drugs[1]. |
|
| DC60502 | GalNAc-Lipid GL6 Featured | GalNAc-Lipid GL6 is a multi-valent N-acetylgalactosamine (GalNAc) targeting ligand. GalNAc-LNP is capable of delivering a CRISPR base editing therapeutic via LDLR-independent pathways. |
|
| DC65965 | Tri-GalNAc(OAc)3 Featured | Tri-GalNAc(OAc)3 is a triantenerrary N-acetylgalactosamine (tri-GalNAc) with an amino group, which is useful precursor for synthesis of GalNAc-LYTAC that engage the asialoglycoprotein receptor for targeted protein degradation. Tri-GalNAc(OAc)3 was first reported in Nat Chem Biol. 2021 Sep;17(9):937-946 (compound ). This product has no formal name at the moment. |
|
| DC66548 | GalNAc-Lipid GL3 Featured |
|
|
| DC66549 | GalNAc-NAG-37 Phosphoramidite Featured |
|
|
| DC66550 | GalNAc-Cluster-COOH Featured |
|
|
| DC66551 | GalNAc-Cluster-HHA-CE Phosphoramidite Featured |
|
|
| DC66555 | GalNAc-L96 Linker-Acid Featured |
|
|
| DC66557 | GalNAc-L96 Linker-Azide Featured |
|
|
| DC66559 | Peracetylated GalNAc PEG linker-Azide Featured |
|
|
| DC66560 | GalNAc-L96-tert-butyl ester Featured | GalNAc-L96-tert-butyl ester is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is also a PEG/Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. |
|
| DC66561 | Peracetylated GalNAc succinimidyl pentanoate Featured |
|
|
| DC66564 | Peracetylated GalNAc PEG linker-Acid-1 Featured |
|
|
| DC66565 | Peracetylated GalNAc-L96-Acid-1 Featured |
|
|
| DC66568 | Peracetylated GalNAc PEG linker-Amino-1 Featured |
|
|
| DC66569 | GalNAc-L96-Amide Featured |
|
|
| DC66572 | Peracetylated GalNAc PEG linker-Amino-2 Featured |
|
|
| DC66574 | Peracetylated GalNAc-L96-1 Featured |
|
|
| DC66575 | Peracetylated GalNAc PEG linker-Acid-2 Featured |
|
