INH1

  Cat. No.:  DC7640  
Chemical Structure
313553-47-8
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More than 5000 active chemicals with high quality for research!
Field of application
INH1 is a cell-permeable Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interaction.
Cas No.: 313553-47-8
Chemical Name: N-[4-(2,4-dimethylphenyl)-2-thiazolyl]-benzamide
Synonyms: INH-1, INH 1
SMILES: CC1C=C(C)C=CC=1C1=CSC(NC(=O)C2C=CC=CC=2)=N1
Formula: C18H16N2Os
M.Wt: 308.4
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: INH1 reduces the association of Hec1 with kinetochore and decreases global Nek2 protein level in cells. INH1 effectively inhibits the proliferation of human breast cancer lines with GI50 of 10-21 μM. Moreover, INH1 also elicits cell killing activity in part through impairing the Hec1/Nek2 pathway For the spindle checkpoint regulation. INH1 (100 mg/kg i.p.) inhibits breast tumor growth in mice bearing MDA-MB-468 human breast cancer xenograft. For the detailed information of INH1, the solubility of INH1 in water, the solubility of INH1 in DMSO, the solubility of INH1 in PBS buffer, the animal experiment (test) of INH1, the cell expriment (test) of INH1, the in vivo, in vitro and clinical trial test of INH1, the EC50, IC50,and Affinity of INH1, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC47243 Dehydroglyasperin C Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
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DC47140 Yadanzioside K Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105 Complanatoside B Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.
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