| DC65710 |
PS13
Featured
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PS13 is a highly potent COX-1 inhibitor (IC50=1 nM) and 1,000 times more selective for COX-1 than COX-2 (7). In non-human primates, 11C-PS13 showed selective binding to COX-1 over COX 2 in most major organs including the spleen, gastrointestinal tract, kidneys, and brain.
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| DC65841 |
MC1
Featured
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MC1 is a selective and potent inhibitor for COX-2, and [11C]MC1 detected COX-2 in nonhuman primates after intracerebral injection of an inflammogen. |
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| DC60608 |
SL25.1188 precursor
Featured
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SL25.1188 precursor is the precursor of SL25.1188.[(11)C]SL25.1188 is a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. |
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| DC60791 |
Cholestify Precursor
Featured
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Precursor of Cholestify,18F-Cholestify, which binds cytochrome P450 46A1, detected cholesterol breakdown in the mammalian brain. CYP46A1 converts cholesterol to 24-hydroxycholesterol, a form easily eliminated from the brain. |
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