DSPE-PEG-N3 is a click chemical PEG reagent. Azide group is easy to react with alkynyl group under the catalysis of copper catalyst. It can also react directly with DBCO without any catalyst. DSPE (1,2-distearoyl-sn-glycerol-3-phosphoethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification. The PEG of phospholipid significantly improved the blood circulation time and stability of the capsule drug. Polyethylene glycol can enhance the solubility and stability, reduce the non-specific binding of charged molecules on the surface, and reduce the immunogenicity of polypeptides. Azide (- N3) can react with copper catalyzed alkynes in aqueous solution and be reduced to amino groups. Polyethylene glycol can increase solubility and stability. It can also inhibit the nonspecific binding of charged molecules on the modified surface.

DSPE-PEG-NBD is a fluorescent phospholipid PEG conjugate, which can be used as a lipid membrane probe. The excitation/emission wavelength of NBD is 460 nm/534 nm.

DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability.

DSPE-PEG(2000)-Amine is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.

mPEG2000-DSPE is used in COVID 19 mRNA vaccines. It is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE . Formulations containing DSPE-MPEG(2000) have been used to prepare liposomes with long circulation time for the delivery of anticancer and antimalarial agents.. mPEG2000-DSPE has also been widely used as hydrophilic surface modifying agent for a variety types of hydrophobic nanoparticles, including recently reported lipid nanoparticle mRNA vaccines.

DSPE-PEG2000-OH is used for creating micelles that are able to carry drugs with low solubility.

DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability.

DOPE-PEG is a versatile phospholipid derivative with unique properties that make it suitable for various applications. Its hydrophobic and hydrophilic nature enables efficient encapsulation and delivery of drugs and nucleic acids, making it a valuable tool in drug delivery systems and gene therapy. Additionally, DOPE-PEG can enhance the stability and circulation time of liposomes, improving their efficacy as drug carriers.

DMG-PEG-Mannose ,1,2-Dimyristoyl-sn-glycerol-methoxypolyethylene glycol-Mannose from kamulin.

DSPE-PEG-Streptavidin is an important biocoupling molecule widely used in biomedical research, especially in drug delivery, targeted therapies, immunodiagnostics and biosensors. Through the specific binding between streptavidin and biotin, DSPE-PEG-Streptavidin can help to achieve efficient loading and targeted action in targeted delivery systems. In addition, the molecule is widely used in molecular imaging and bioassays, especially for molecular recognition using the strong affinity between streptavidin and biotin in assay platforms that require high sensitivity and specificity.

DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research.

TAMRA-PEG4-NHS ester is a TAMRA red fluorescent dye derivative containing an NHS ester group which can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

DSPE-PEG-TCO (2000 Da) is a functionalized polyethylene glycol lipid conjugate engineered to enhance drug delivery systems. This amphiphilic polymer-lipid hybrid demonstrates unique capabilities in optimizing the bioavailability and targeted distribution of hydrophobic therapeutic compounds. Its molecular architecture combines a lipid anchor with a biocompatible PEG chain terminated by a trans-cyclooctene (TCO) group, enabling precise tissue-specific interactions while improving pharmacokinetic profiles. Researchers frequently employ this advanced biomaterial in developing nanoparticle formulations and ligand-directed therapeutic platforms for enhanced precision medicine applications.

The transferrin receptor (TfR) is a transmembrane glycoprotein whose function is to mediate iron absorption through its interaction with transferrin. In normal cells, the expression level of the receptor is low, and the expression of the transferrin receptor in cells (chronic lymphocytic non-Hodgkin tumors) is significantly increased due to the increased demand for iron in rapidly growing cells [2-4]. At present, two transferrin receptors, TfR1 and TfR2, have been found, both of which are type II transmembrane glycoproteins that bind to transferrin and mediate iron absorption. TfR1 is expressed in many cells (such as red blood cells, hepatocytes, monocytes), and can change its conformation according to the change of environmental pH, and convert the results of conformational change into a change in the binding strength of transferrin. TfR2 is mainly expressed in the liver, and its main function may be to regulate and maintain the homeostasis of iron ions in the body, while its role in transporting iron ions to rapidly dividing tissues is weak. Using the effective targeting function of transferrin receptor, the cross-linking of transferrin and drugs can improve the specific binding ability of drugs, but also improve the effect.

Glucose, organic compound, molecular formula C6H12O6. It is one of the most widely distributed and important monosaccharides in nature, and it is a polyhydroxyaldehyde. Glucose plays an important role in the field of biology, that is, the main energy supplier of living things. Plants produce glucose through photosynthesis. Liposome has the advantages of low toxicity, easy preparation, as a carrier of both water-soluble and fat-soluble drugs, suitable for a variety of drug delivery routes, improve drug stability, and achieve targeted drug delivery. However, after the liposome enters the body, it is easy to be taken up and cleared by RES cells due to the specific conditioning effect of opsonins in plasma on the liposome and the non-specific hydrophobic interaction between RES cells and liposome.

DSPE-PEG(2000)-amine is a PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE (DSPE; Item No. 15095). It has been used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents. DSPE-PEG(2000)-amine has also been used in the synthesis of fluorescein isothiocyanate-loaded mesoporous silica nanoparticles for imaging applications.4 It can be conjugated to a variety of functional molecules for improved cellular targeting and uptake of DSPE-PEG(2000)-amine-containing nanoparticles.

DSPE-PEG2K-triGalNAc is a polar lipid composed of DSPE and tri-N-acetylgalactosamine that can be used to construct liposomes target to asialoglycoprotein receptor (ASGPR).

DSPE-PEG-Maleimide, MW 2,000 is a PEG compound with DSPE and maleimide groups. The DSPE-PEGs have been FDA approved for medical applications. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic polyPEG increases the water solubility of the overall compound allowing for the delivery of the drug. Maleimide groups can react with thiol groups between pH 6.5 to 7.5.

DSPE-Hyd-PEG, also known as distearoylphosphoethanolamine-hydrazide-polyethylene glycol, is a type of lipid-based polymer that has various applications in drug delivery and biomedical research. One of the main applications of DSPE-Hyd-PEG is in the field of targeted drug delivery. It is often used as a component of liposomes or lipid nanoparticles to improve the stability and targeting ability of drug carriers. DSPE-Hyd-PEG can be conjugated with targeting ligands, such as antibodies or peptides, to specifically bind to receptors on the surface of target cells. This targeted drug delivery system allows for more efficient and selective delivery of therapeutic agents to the desired site, while minimizing off-target effects.

DSPE-PEG-Biotin (MW 1000) is a PEG-based PROTAC linker

The phospholipid polyethylene glycol alkyne (DSPE PEG Alkyne) can be used to modify proteins, peptides and other materials or small molecules. Alkynyl (- ALK) can react with copper catalyzed azide in aqueous solution. 2-Distearoyl-sn-Glycero-3-Phosphoethanolamine (DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol with hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes form high-quality materials, which can be used for drug delivery, gene transfection and vaccine delivery. PEGylated phospholipid can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides.

DSPE-m-PEG-NHS (MW 3400) is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine.

DSPE-Hyd-PEG, also known as distearoylphosphoethanolamine-hydrazide-polyethylene glycol, is a type of lipid-based polymer that has various applications in drug delivery and biomedical research. One of the main applications of DSPE-Hyd-PEG is in the field of targeted drug delivery. It is often used as a component of liposomes or lipid nanoparticles to improve the stability and targeting ability of drug carriers. DSPE-Hyd-PEG can be conjugated with targeting ligands, such as antibodies or peptides, to specifically bind to receptors on the surface of target cells. This targeted drug delivery system allows for more efficient and selective delivery of therapeutic agents to the desired site, while minimizing off-target effects.

The molecules can be labeled in the aqueous phase without organic solvents. Therefore, the product is especially suitable for labeling proteins that are easily denatured in the organic phase and proteins with low solubility. Polyethylene glycol phospholipid liposomes form high-quality materials, which can be used for drug delivery, gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying surface ligands such as antibodies and peptides. (DSPE) conjugated polyethylene glycol is a combination of phospholipids and polyethylene glycol, which has hydrophilicity and hydrophobicity. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces, such as antibodies and peptides. Cyanogen dye cyanine is often used in biomolecular labeling, fluorescence imaging and other fluorescent biological analysis. Cy5 (sulfo-cyanine5) is a reactive dye used to label amino groups of peptides, proteins and oligonucleotides. Excitation wavelength (nm): 649, emission wavelength (nm): 670.

DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.

DSPE-PEG-CLS is a phospholipid PEG derivative used in liposome preparation, phospholipid polyethylene glycol binding with hydrophilic and hydrophobic, polyethylene glycol phospholipid liposome formation material, which can be used for drug delivery, gene transfection and vaccine delivery. Cholesterol is the basic substance of cell membrane and liposome, is also an indispensable important substance of animal tissue cells, it not only participates in the formation of cell membrane, but also is the raw material of synthesis of bile acid, vitamin D and steroid hormone.

The affinity between lactoferrin and iron ion is very high, which is 250 to 300 times that of transferrin. According to the difference of lactoferrin binding iron ions, it can be divided into three types: iron deficiency type, iron semi-satiation type and iron saturated type. Different types of lactoferrin have different ability to resist pasteurization thermal denaturation, in which iron saturated type resistance is strong, iron deficiency type resistance is weak. Lactoferrin can bind not only Fe3+ and Fe2+, but also Cu2+, Mn2+ and Zn2+.

DSPE-Hyd-PEG, also known as distearoylphosphoethanolamine-hydrazide-polyethylene glycol, is a type of lipid-based polymer that has various applications in drug delivery and biomedical research. One of the main applications of DSPE-Hyd-PEG is in the field of targeted drug delivery. It is often used as a component of liposomes or lipid nanoparticles to improve the stability and targeting ability of drug carriers. DSPE-Hyd-PEG can be conjugated with targeting ligands, such as antibodies or peptides, to specifically bind to receptors on the surface of target cells. This targeted drug delivery system allows for more efficient and selective delivery of therapeutic agents to the desired site, while minimizing off-target effects.

DSPE-Hyd-PEG, also known as distearoylphosphoethanolamine-hydrazide-polyethylene glycol, is a type of lipid-based polymer that has various applications in drug delivery and biomedical research. One of the main applications of DSPE-Hyd-PEG is in the field of targeted drug delivery. It is often used as a component of liposomes or lipid nanoparticles to improve the stability and targeting ability of drug carriers. DSPE-Hyd-PEG can be conjugated with targeting ligands, such as antibodies or peptides, to specifically bind to receptors on the surface of target cells. This targeted drug delivery system allows for more efficient and selective delivery of therapeutic agents to the desired site, while minimizing off-target effects.