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Functionalized Lipids

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Cat. No. Product Name Field of Application Chemical Structure
DC67096 DMG-PEG2000-NHS Featured
DMG-PEG2000-NHS is a PEG derivative that can be used in various biomedical applications, such as the construction of drug delivery systems (siRNA delivery liposomes, lipid nanoparticle, etc.). The active ester (NHS) can react with an amino group (-NH2) to form a stable amide bond, which can be used as a linker in a bioconjugation strategy to modify amino-linked peptide proteins as well as other small molecules.
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DC66097 DSPE-RB Featured
Phospholipids DSPE belong to the lipid family of biopolymers. Phospholipids consist of two fatty acids, a glycerol unit, a phosphate group, and a polar molecule. The phosphate groups and polar head regions of the molecule are hydrophilic (attracted to water), while the fatty acid tail is hydrophobic (repelled by water). When placed in water, the phospholipids Orient themselves into a double layer, where the non-polar tail region faces the inner region of the double layer. The polar head region faces outward and interacts with the water. Applications in drug release, nanotechnology and new materials research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and pegylated modified functional coatings and other active compounds.
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DC66102 DSPE-SH(DSPE Thiol) Featured
Modified phospholipid products: it is to modify the amino group (primary amino group) -NH3 at the end of DSPE into NHS, COOH, N3, MAL, Thiol (SH), OPSS, FITC, FA, Biotin and other different active groups. Phospholipids DSPE belong to the lipid family of biopolymers. Phospholipids consist of two fatty acids, a glycerol unit, a phosphate group, and a polar molecule. The phosphate groups and polar head regions of the molecule are hydrophilic (attracted to water), while the fatty acid tail is hydrophobic (repelled by water). When placed in water, the phospholipids Orient themselves into a double layer, where the non-polar tail region faces the inner region of the double layer. The polar head region faces outward and interacts with the water.
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DC66103 DSPE-NH2 Featured
Phosphatidyl amino DSPE-NH2 is one of the most common materials in polymer modification. By grafting phospholipid bonds to amino molecules, polymeric polymers with different chain segments are formed by using phospholipid molecules, which reduces the thermal stability and weather resistance of the materials. At the same time, by introducing modifiers to improve the water resistance of the polymer itself, improve its processing performance, and finally obtain good water resistance, high mechanical properties, good weather resistance, good acid and alkali resistance products. DSPE-NH2 material is mainly composed of isopropyl alcohol butadiene, the isopropyl alcohol butadiene mixture is an aromatic polymer, with strong water absorption, hydrophilicity, and wide molecular weight distribution, good solubility, high mechanical strength characteristics, so the material can be used in many fields.
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DC66105 DSPE-PEI Featured
DC66095 DSPE-CY5 Featured
Phospholipids DSPE belong to the lipid family of biopolymers. Phospholipids consist of two fatty acids, a glycerol unit, a phosphate group, and a polar molecule. The phosphate groups and polar head regions of the molecule are hydrophilic (attracted to water), while the fatty acid tail is hydrophobic (repelled by water). When placed in water, the phospholipids Orient themselves into a double layer, where the non-polar tail region faces the inner region of the double layer. The polar head region faces outward and interacts with the water. Applications in drug release, nanotechnology and new materials research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and pegylated modified functional coatings and other active compounds.
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DC66093 DSPE-CY7 Featured
Phospholipids DSPE belong to the lipid family of biopolymers. Phospholipids consist of two fatty acids, a glycerol unit, a phosphate group, and a polar molecule. The phosphate groups and polar head regions of the molecule are hydrophilic (attracted to water), while the fatty acid tail is hydrophobic (repelled by water). When placed in water, the phospholipids Orient themselves into a double layer, where the non-polar tail region faces the inner region of the double layer. The polar head region faces outward and interacts with the water. Applications in drug release, nanotechnology and new materials research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and pegylated modified functional coatings and other active compounds.
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DC66098 DSPE-FITC Featured
Phospholipids DSPE belong to the lipid family of biopolymers. Phospholipids consist of two fatty acids, a glycerol unit, a phosphate group, and a polar molecule. The phosphate groups and polar head regions of the molecule are hydrophilic (attracted to water), while the fatty acid tail is hydrophobic (repelled by water). When placed in water, the phospholipids Orient themselves into a double layer, where the non-polar tail region faces the inner region of the double layer. The polar head region faces outward and interacts with the water. Applications in drug release, nanotechnology and new materials research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and pegylated modified functional coatings and other active compounds.
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DC66101 DSPE-COOH Featured
DC66119 DSPE-MPEG Featured
2-Distearoyl-sn-Glycero-3-Phosphoethanolamine(DSPE) conjugated polyethylene glycol is a combination of phospholipid and polyethylene glycol, which has hydrophilicity and hydrophobicity. Polyethylene glycol phospholipid liposomes can be used for drug delivery, gene transfection and vaccine delivery. Pegylated phospholipids can significantly improve blood circulation time and stabilize drug encapsulation. These materials can also be used for targeted drug delivery by modifying ligands with target surfaces such as antibodies and peptides,Liposomes.
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DC66278 DSPE-PEG-AC Featured
DSPE-PEG-AC phospholipid PEG derivative used in the preparation of liposomes, phospholipatized polyethylene glycol binding has both hydrophilic and hydrophobic properties. Acrylate functionalized PEG is a common polymer for preparing biocompatible and biodegradable hydrogels and other biopolymers. Functionalized polyethylene glycol can be used to modify proteins, peptides, and materials, but also to increase solubility and stability, and reduce peptide and protein immunogenicity. It can also inhibit the non-specific combination of charged molecules to modify the surface. The product can be used in drug release, nanotechnology and new materials research, cell culture. As well as ligand research, peptide synthesis support, grafted polymer compounds, new materials and pegylated modified functional coatings and other active compounds.
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DC66273 DSPE-PEG-CHO Featured
DSPE phospholipids can be used as pharmaceutical excipients for emulsification and drug solubilization, and are important materials for slow release drug preparations such as liposomes, fat milk and nanoparticles in recent years. Modification of phospholipid molecules can make these preparations have the ability of release and targeting under specific conditions. Common modification methods include: disintegration time; Introducing immune factors to enhance targeting; Introduce markers for diagnosis and tracking. A covalent bond in the carbonyl group is connected to the hydrogen atom and formed by a univalent atomic group, called aldehyde group, aldehyde group structure simple formula is -CHO, aldehyde group is a hydrophilic group, so the organic matter with aldehyde group (such as acetaldehyde, etc.) has a certain water solubility. Aldehydes, sugars, aldehydes, glucose, maltose and other molecules contain aldehyde groups. The aldehydes are active and prone to condensation and nucleophilic addition reactions. The aldehyde group can be reduced to hydroxymethyl (-CH2OH) or oxidized to carboxylic (-COOH).
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DC66163 DSPE-PEG-RGD Featured
RGD's receptors are integrins αvβ3 and αvβ5, which can mimic cell adhesion proteins and bind specifically to 11 kinds of integrins, which can effectively adhere to biological materials. DSPE-PEG-RGD can be used to make micelles and vesicles. The liposomes formed by RGD-PEG-DSPE can act directly on the target to form an active targeting effect. Rgd-peg-dspe peptide RGD polyethylene glycol phospholipid can be used for passive targeting of micelles and vesicles, active targeting research and drug delivery. DSPE (1, 2-distearoyl-SN-glycerol-3-phosphate ethanolamine) is a saturated 18-carbon phospholipid commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) -coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection, and biomolecular modification. Polyethylene glycol can enhance solubility and stability, reduce the nonspecific binding of charged molecules, and reduce the immunogenicity of polypeptides.
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DC66168 DSPE-PEG-ICG Featured
DSPE phospholipids can be used as pharmaceutical excipients for emulsification and drug solubilization, and are important materials for slow release drug preparations such as liposomes, fat milk and nanoparticles in recent years. Modification of phospholipid molecules can make these preparations have the ability of release and targeting under specific conditions. Common modification methods include: disintegration time; Introducing immune factors to enhance targeting; Introduce markers for diagnosis and tracking.
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DC66295 DSPE-PEG-CY7 Featured
Polyethylene glycol phospholipid is an excellent material to form liposomes, which can be used for gene transfection, vaccine delivery, drug transportation, and targeted drug delivery. Phospholipids are hydrophobic and hydrophilic. It can be used to modify protein drugs, peptide compounds, organic small molecule drugs, biological materials, etc. Cy7 labeled PEG derivatives are used for fluorescence tracing or fluorescence observation.
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DC66292 DSPE-PEG-NPC Featured
DSPE-PEG-NPC is a linear heterobifunctional polyglycolation reagent containing DSPE phospholipids and NPC groups. It is a useful self-assembly reagent for preparing PEGylated liposomes or micelles, and also provides a combination of NPC group and thiol containing molecules.
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DC66116 DSPE-PEG-FITC Featured
DSPE-PEG-FITC, is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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DC66291 DSPE-PEG-OPSS Featured
DSPE-PEG-OPSS, DSPE (1,2-distearoyl-sn-glycerol-3-phosphoethanolamine) is a saturated 18 carbon phospholipid, commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification. The PEG of phospholipid significantly improved the blood circulation time and stability of the capsule drug. Polyethylene glycol can enhance the solubility and stability, reduce the non-specific binding of charged molecules on the surface, and reduce the immunogenicity of polypeptides. Mercaptopyridine reacts with mercapto group to release pyridine ring and generate stable disulfide bond.
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DC66280 DSPE-PEG-DOTA Featured
Macrocyclic ligands are ring complexes formed by multi-dentate ligands with O, N, P, S and other coordination atoms on the ring skeleton. The range of complexes is wide. According to their structural characteristics, complexes can be divided into the following types: simple complexes, chelates, polynuclear complexes, carbonyl complexes, metal clusters, sandwich complexes, and macrocyclic ligand complexes.
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DC66106 DSPE-Maleimide Featured
DC66290 DSPE-PEG-Mannose Featured
DSPE (1,2-distearoyl-sn glycerol-3-phosphoethanolamine) is a saturated 18C phospholipid commonly used in liposome synthesis. Polyethylene glycol (PEG) conjugated DSPE has hydrophilicity and hydrophobicity, and can be used for drug delivery, gene transfection, and biomolecular modification. DSPE-PEG-Manose can be applied in medical research, drug release, nanotechnology and new material research, and cell culture. As well as ligand research, peptide synthesis support, grafting of polymer compounds, new materials, and polyethylene glycol modified functional coatings and other active compounds.
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DC66117 DSPE-PEG-Rhodamine Featured
DSPE-PEG-FITC is a fluorescein attached PEG lipid. It can be used to prepare liposomes as drug carrier in targeted drug delivery. The polymer is modified with fluorescein (green) dye which can be used for staining cells, tissues, biomarkers, or nanoparticles.
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DC66118 DSPE-PEG-Galactose Featured
Long circulating liposomes were obtained by modifying the surface of liposomes with polyethylene glycol, which could prolong the half-life of liposomes, improve its stability in blood circulation, and change the biological distribution of liposomes.
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DC66276 DSPE-PEG-Cholesterol Featured
DSPE-PEG-CLS is a phospholipid PEG derivative used in liposome preparation, phospholipid polyethylene glycol binding with hydrophilic and hydrophobic, polyethylene glycol phospholipid liposome formation material, which can be used for drug delivery, gene transfection and vaccine delivery. Cholesterol is the basic substance of cell membrane and liposome, is also an indispensable important substance of animal tissue cells, it not only participates in the formation of cell membrane, but also is the raw material of synthesis of bile acid, vitamin D and steroid hormone.
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DC66166 DSPE-PEG-Glucose;DSPE-PEG2000-Glucose Featured
Glucose, organic compound, molecular formula C6H12O6. It is one of the most widely distributed and important monosaccharides in nature, and it is a polyhydroxyaldehyde. Glucose plays an important role in the field of biology, that is, the main energy supplier of living things. Plants produce glucose through photosynthesis. Liposome has the advantages of low toxicity, easy preparation, as a carrier of both water-soluble and fat-soluble drugs, suitable for a variety of drug delivery routes, improve drug stability, and achieve targeted drug delivery. However, after the liposome enters the body, it is easy to be taken up and cleared by RES cells due to the specific conditioning effect of opsonins in plasma on the liposome and the non-specific hydrophobic interaction between RES cells and liposome.
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DC80023 DSPE-PEG2000-DBCO Featured
DSPE-PEG-DBCO ammonium is the ammonium salt form of DSPE-PEG-DBCO. DSPE-PEG-DBCO ammonium is utilized in copper-free click chemistry through SPAAC conjugation with an azido-functionalized peptide ligand. DSPE-PEG-DBCO ammonium is applied in drug-delivery and nanoparticle research.
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DC67571 DMG-PEG-Mannose Featured
DMG-PEG-Mannose is a specialized functionalized lipid used primarily for the targeted delivery of lipid nanoparticles (LNPs) and liposomes to cells expressing mannose receptors, such as macrophages and dendritic cells. It combines a 1,2-dimyristoyl-sn-glycerol (DMG) lipid anchor with a polyethylene glycol (PEG) spacer and a terminal mannose sugar moiety.
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DC66199 DMPE-PEG-NBD (PEG2000) Featured
DMPE-PEG, a synthetic lipid, possesses unique properties and finds extensive applications as liposomes. Firstly, DMPE-PEG exhibits excellent biocompatibility and solubility, allowing for its stable presence and efficient absorption and metabolism in vivo. Additionally, DMPE-PEG possesses good surface activity, aiding in the stabilization of liposome structures and enhancing their stability.
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DC66294 DSPE-PEG-NBD(PEG2000) Featured
DSPE-PEG-NBD is a fluorescent phospholipid PEG conjugate, which can be used as a lipid membrane probe. The excitation/emission wavelength of NBD is 460 nm/534 nm.
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DC66293 DSPE-PEG-N3(DSPE-PEG-Azide, MW2000) Featured
DSPE-PEG-N3 is a click chemical PEG reagent. Azide group is easy to react with alkynyl group under the catalysis of copper catalyst. It can also react directly with DBCO without any catalyst. DSPE (1,2-distearoyl-sn-glycerol-3-phosphoethanolamine) is a saturated 18 carbon phospholipid, which is commonly used in the synthesis of liposomes. Polyethylene glycol (PEG) - coupled DSPE is hydrophilic and can be used for drug delivery, gene transfection and biomolecular modification. The PEG of phospholipid significantly improved the blood circulation time and stability of the capsule drug. Polyethylene glycol can enhance the solubility and stability, reduce the non-specific binding of charged molecules on the surface, and reduce the immunogenicity of polypeptides. Azide (- N3) can react with copper catalyzed alkynes in aqueous solution and be reduced to amino groups. Polyethylene glycol can increase solubility and stability. It can also inhibit the nonspecific binding of charged molecules on the modified surface.
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