Isavuconazole

  Cat. No.:  DC8120  
Chemical Structure
241479-67-4
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More than 5000 active chemicals with high quality for research!
Field of application
Isavuconazole(BAL-4815; RO-0094815) is the active component of the new azole antifungal agent BAL8557, exhibits MIC(50)s/MIC(90)s ranged from 0.002/0.004 mg/liter for C. albicans to 0.25/0.5 mg/liter for C. glabrata.
Cas No.: 241479-67-4
Chemical Name: 4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile
Synonyms: Isavuconazole
SMILES: FC1=CC=C(F)C=C1[C@](CN2C=NC=N2)(O)[C@@H](C)C3=NC(C4=CC=C(C#N)C=C4)=CS3
Formula: C22H17F2N5Os
M.Wt: 437.47
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Isavuconazole was more active (0.004 mg/liter) than amphotericin B (0.5 mg/liter), itraconazole (0.008 mg/liter), voriconazole (0.03 mg/liter), flucytosine (0.125 mg/liter), and fluconazole (8 mg/liter). There were only two isolates with MICs for isavuconazole that were >0.5 mg/liter: both were C. glabrata isolates, and the MICs were 2 and 4 mg/liter, respectively. Isavuconazole has MIC90 value of 0.016 microg/ml against Cryptococcus neoformans isolates from Cuba. For the detailed information of Isavuconazole, the solubility of Isavuconazole in water, the solubility of Isavuconazole in DMSO, the solubility of Isavuconazole in PBS buffer, the animal experiment (test) of Isavuconazole, the cell expriment (test) of Isavuconazole, the in vivo, in vitro and clinical trial test of Isavuconazole, the EC50, IC50,and affinity,of Isavuconazole, For the detailed information of Isavuconazole, the solubility of Isavuconazole in water, the solubility of Isavuconazole in DMSO, the solubility of Isavuconazole in PBS buffer, the animal experiment (test) of Isavuconazole, the cell expriment (test) of Isavuconazole, the in vivo, in vitro and clinical trial test of Isavuconazole, the EC50, IC50,and affinity,of Isavuconazole, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC47247 Tyrosylleucine TFA Tyrosylleucine (Tyr-Leu, YL) TFA, an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47243 Dehydroglyasperin C Dehydroglyasperin C, a isoflavone, is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C has antioxidant, neuroprotective, cancer chemopreventive, and anti-inflammatory activities.
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DC47224 GPX4-IN-3 GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
DC47179 Tyrosylleucine Tyrosylleucine (Tyr-Leu, YL), an orally active dipeptide, exhibits a potent antidepressant-like activity.
DC47178 Mead acid Mead acid (5,8,11-Eicosatrienoic acid), an unsaturated (Omega-9) fatty acid, is an indicator of essential fatty acid deficiency.
DC47140 Yadanzioside K Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105 Complanatoside B Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.
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