Cas No.: | 374559-48-5 |
Chemical Name: | (3E,5S,8R,9S,10R,13S,14S)-3-(2-Aminoethoxyimino)-10,13-dimethyl-1,2,4,5,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-6,17-dione Hydrochloride |
Synonyms: | Istaroxime HCl; PST2744; PST 2744; PST-2744; PST-2744 HCl; PST-2744 hydrochloride |
SMILES: | C[C@]12CC/C(=N\OCCN)/C[C@@H]1C(=O)C[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C.Cl |
Formula: | C21H33ClN2O3 |
M.Wt: | 396.956 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Istaroxime is a positive inotropic agent that mediates its action through inhibition of sodium/potassium adenosine triphosphatase (Na+/K+ ATPase). Istaroxime is an investigational drug originally patented and developed by the italian pharmaceutical company Sigma-Tau. Istaroxime is now under development for treatment of acute decompensated heart failure by CVie Therapeutics. For the detailed information of PST2774, the solubility of PST2774 in water, the solubility of PST2774 in DMSO, the solubility of PST2774 in PBS buffer, the animal experiment (test) of PST2774, the cell expriment (test) of PST2774, the in vivo, in vitro and clinical trial test of PST2774, the EC50, IC50,and affinity,of PST2774, Please contact DC Chemicals. |