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Mucrolidin

  Cat. No.:  DC41350  
Chemical Structure
227471-20-7
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More than 5000 active chemicals with high quality for research!
Field of application
Mucrolidin is an eudesmane-type sesquiterpenoid isolated from aerial parts of homalomena occulta. Mucrolidin exhibits weak antibacterial activities when it compares to Rifampicin.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 227471-20-7
Chemical Name: Mucrolidin
Synonyms: 1,4,5-Naphthalenetriol,decahydro-4,8a-dimethyl-6-(1-methylethyl)-, (1R,4S,4aS,5S,6S,8aR)-;Mucrolidin;(1R,4S,4aS,5S,6S,8aR)-6-Isopropyl-4,8a-dimethyldecahydro-1,4,5-na phthalenetriol;(+)-1b,4b,6a-Trihydroxyeudesmane;(+)-1beta,4beta,6alpha-Trihydroxyeudesmane;[ "1", "4", "6-Eudesmanetriol" ];4,8a-Dimethyl-6-propan-2-yl-1,2,3,4a,5,6,7,8-octahydronaphthalene-1,4,5-triol
SMILES: O([H])C1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C2(C([H])([H])[H])C([H])([H])C([H])([H])C([H])(C([H])(C([H])([H])[H])C([H])([H])[H])C([H])(C21[H])O[H])O[H]
Formula: C15H28O3
M.Wt: 256.3810
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_24363_DC41350_227471-20-7
COA
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Cat. No. Product name Field of application
DC72935 JSF-2414 JSF-2414 (JSF2414) is a potent, small molecule GyrB/ParE dual binding inhibitor, simultaneously binds to ATP binding regions of DNA gyrase (GyrB) and topoisomerase (ParE) and displays potent in vitro activity against strains of MRSA, VRSA and VISA.
DC72568 Cymal-6 Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) is a potent TEM-1 beta-lactamase inhibitor with an Ki value of 40.05 µM. Cymal-6 (Cyclohexyl-hexyl-β-D-maltoside) can be used as glycosidic surfactant.
DC72280 PNU-101603 PNU-101603 is a metabolite of Sutezolid. PNU-101603 has excellent activity against Mycobacterium tuberculosis (MTB).
DC72144 TH-Z145 TH-Z145, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 210 nM).
DC72008 UNC10201652 UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes.
DC71474 VP-4604 VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. VP-4604 exhibits significant microbial growth inhibition toward Staphylococcus aureus (ATCC 43300) with MIC of 4-8 µg/mL. VP-4604 inhibits the growth of methicillin‐resistant Staphylococcus aureus with growth inhibition >95%.
DC71466 EDA-DA EDA-DA is an unnatural dipeptide building block (an ethynyl-D-alanine and a D-alanine). It incorporates a biorthogonal alkyne group into peptidoglycan (PG) through MurF in the cytoplasmic pathway, which enables selective labeling via a click-chemistry reaction. EDA-DA allows labeling of PG in Gram-positive (B. subtilis), Gram-negative (E. coli and C. trachomatis), Mycobacterium (M. smegmatis) and moss plastids (P. patens) with azide modified fluorescent dyes such as Alexa Fluor 488.
DC70750 Rv1625c agonist V-59 Rv1625c agonist V-59 (V-59) is a specific small molecule agonist of the Mtb adenylyl cyclase Rv1625c, inhibits Mtb growth in macrophages (EC50=0.3 uM) in an Rv1625c-dependent mechanism.V-59 inhibits Mtb growth in cholesterol media (EC50 0.70 uM), but not in media containing the two-carbon fatty acid acetate, or in standard rich growth media.V-59 stimulates Rv1625c to produce cAMP, which is necessary for V-59 to inhibit Mtb growth.Chemically activating Rv1625c via V-59 preferentially inhibits cholesterol utilization in WT Mtb, rather than equally inhibiting all lipid utilization by the bacterium.
DC70459 GSK3011724A GSK 3011724A (DG-167, GSK-3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM), shows anti-tubercular activity (MIC H37Rv=0.8 uM); shows much weaker apparent dissociation constant for both Pks10 and Pks (Kd=1.4 uM); inhibits mycolic acid biosynthesis and shows negligible activity against a panel of unrelated proteins and 18 Gram-positive and Gram-negative bacterial species.
DC70368 DU011 DU011 is a noncanonical anti-infective agent and small-molecule inhibitor of capsule biogenesis, targets MprA (Kd=30 nM), a MarR family transcriptional repressor of multidrug efflux pumps, inhibits capsule expression in E. coli. DU011 does not alter Escherichia coli antibiotic resistance and has significantly enhanced inhibition of capsule expression, compared with other proposed MprA ligands, such as salicylate and 2,4-dinitrophenol (DNP).
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