(R)-Equol

  Cat. No.:  DC8450  
Chemical Structure
221054-79-1
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Field of application
In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ERα and ERβ with Ki values of 27.4 and 15.4 nM, respectively.
Cas No.: 221054-79-1
Chemical Name: 3,4-dihydro-3R-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
Synonyms: Isoequol
SMILES: OC1=CC2=C(C=C1)C[C@H](C3=CC=C(O)C=C3)CO2
Formula: C15H14O3
M.Wt: 242.3
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora.It is a chiral molecule that exists in two enantiomeric forms.In contrast to the estrogen receptor (ER) selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ERα and ERβ with Ki values of 27.4 and 15.4 nM, respectively.The (R)-enantiomer demonstrates higher ER agonist activity at ERα compared to ERβ (EC50 = 66 and 330 nM, respectively). For the detailed information of (R)-Equol, the solubility of (R)-Equol in water, the solubility of (R)-Equol in DMSO, the solubility of (R)-Equol in PBS buffer, the animal experiment (test) of (R)-Equol, the cell expriment (test) of (R)-Equol, the in vivo, in vitro and clinical trial test of (R)-Equol, the EC50, IC50,and affinity,of (R)-Equol, For the detailed information of (R)-Equol, the solubility of (R)-Equol in water, the solubility of (R)-Equol in DMSO, the solubility of (R)-Equol in PBS buffer, the animal experiment (test) of (R)-Equol, the cell expriment (test) of (R)-Equol, the in vivo, in vitro and clinical trial test of (R)-Equol, the EC50, IC50,and affinity,of (R)-Equol, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC47224 GPX4-IN-3 GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 μM.
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DC47140 Yadanzioside K Yadanzioside K is a natural quassinoid glucoside found in Brucea amarissima.
DC47105 Complanatoside B Complanatoside B is a P. chinense Fisch flavonoid with potential anti-inflammatory effects.
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