| DCZ-292 |
TECTOCHRYSIN |
purity >98%,Standard References |
|
| DCZ-290 |
Isobavachin |
purity >98%,Standard References |
|
| DCZ-286 |
8-GERANOPSORALEN |
purity >98%,Standard References |
|
| DCZ-289 |
songorine |
purity >98%,Standard References |
|
| DC7501 |
SKLB1002
Featured
|
SKLB1002 is a novel and potent VEGFR-2 inhibitor with an IC50 value of 32 nM. |
|
| DCC-003 |
Vincristine |
>98%,Standard References |
|
| DC60202 |
YUN35454
Featured
|
YUN35454, also known as LMPTP INHIBITOR 1 is a selective inhibitor of low molecular weight protein tyrosine phosphatase (LMPTP), with an IC50 of 0.8 μM LMPTP-A. LMPTP is a key promoter of insulin resistance and that LMPTP inhibitors would be beneficial for treating type 2 diabetes. YUN35454 was first reported in Nature Chemical Biology (2017), 13(6), 624-632. |
|
| DC60203 |
JNJ-63576253 HCl
Featured
|
JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically binds to both wild-type and certain mutant forms of AR, thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. |
|
| DC50005 |
CH7233163 |
CH7233163 is a novel selective inhibitor of various types of EGFR mutants including L858R/T790M/C797S, L858R/T790M, Del19/T790M, Del19, and L858R, showing potent antitumor activities |
|
| DC50006 |
Cinobufagin (Cinobufagine)
Featured
|
Cinobufagin, a kind of Chinese materia medica with antitumor effect, is widely used in clinical practice, especially in anti-liver cancer. IC50 value: Target: In vitro: Cinobufagin inhibited proliferation of cancer cells at doses of 0.1, 1, or 10 μM after 2–4 days of culture. Cytotoxicity of cinobufagin on the DU145 and LNCaP cells was dose-dependent. Cinobufagin increased [Ca2+]i and apoptosis in cancer cells after a 24-hr culture as well as caspase 3 activities in DU145 and PC3 cells and caspase 9 activities in LNCaP cells [1]. Cinobufagin suppresses cell proliferation and causees apoptosis in prostate cancer cells via a sequence of apoptotic modulators, including Bax, cytochrome c and caspases [2]. |
|
| DC50007 |
Etoposide
Featured
|
>98%,Standard References |
|
| DC50008 |
Colchicine
Featured
|
Colchicine is a potent therapeutic tool against COVID-19. Colchicine is a tricyclic alkaloid that is extracted from the plant Colchicum autumnale. Colchicine acts as a potent inhibitor of tubulin polymerization. |
|
| DC83215 |
DMAP-BLP |
DMAP-BLP is a lipid for RNA and vaccine delivery.DMAP-BLP exhibits optimized bilayer destabilizing and pKa properties leading to highly potent gene silencing in hepatocytes following IV administration that is similar to “gold standard” lipids such as DLinMC3-DMA. |
|
