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JNJ-63576253 HCl

  Cat. No.:  DC60203   Featured
Chemical Structure
2110428-64-1
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More than 5000 active chemicals with high quality for research!
Field of application
JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically binds to both wild-type and certain mutant forms of AR, thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2110428-64-1
Chemical Name: JNJ-63576253 HCl
Synonyms: JNJ-63576253;s9900;JNJ-63576253 HCl
SMILES: Cl[H].S=C1N(C2C([H])=NC(C#N)=C(C(F)(F)F)C=2[H])C(C2(C([H])([H])C([H])([H])C2([H])[H])N1C1=C([H])N=C(C([H])=C1[H])OC1([H])C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])=O
Formula: C23H22ClF3N6O2S
M.Wt: 538.9730
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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DC60203 JNJ-63576253 HCl JNJ63576253, also known as TRC253, is a potent and orally active androgen receptor antagonist. TRC253 specifically binds to both wild-type and certain mutant forms of AR, thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus.
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