| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC21864 | Ack1 inhibitor 37 | Ack1 inhibitor 37 is a potent and selective Ack1 (TNK2) inhibitor with Ki of 0.3 nM, displays high selectivity over related kinases LCK, JAK3, KDR and TIE2 (Ki= 138, 6.5, 380 and 200 nM). |
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| DC11356 | Caspase-9 Chromogenic Substrate I | Ac-LEHD-pNA is a substrate for caspase-9.1 Caspase-9 preferentially binds to and cleaves the Leu-Glu-His-Asp (LEHD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. |
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| DC23795 | ACO1 | ACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM, displays >200-fold selectivity against other Hsp90 isoforms. |
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| DC7354 | Acolbifene | acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 (SCH 57068) and the prodrug EM-800 ( |
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| DC10279 | Acrivastine | Acrivastine (BW825C) is a short acting histamine 1 receptor antagonist for the treatment of allergic rhinitis. |
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| DC20640 | ACT 709478 | ACT 709478 is a potent, selective, orally-bioavailable, brain penetrant T-type calcium channel blocker with IC50 of 6.4, 18, and 7.5 nM for Cav3.1, Cav3.2, and Cav3.3 channels respectively. |
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| DC11209 | ACT-246475 | ACT-246475 (ACT246475) is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
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| DC21986 | ACT-281959 | ACT-281959 (ACT281959) is the prodrug of ACT-246475, which is a potent, selective, reversible P2Y12 receptor antagonist with binding IC50 of 1.0 nM. |
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| DC11439 | Nemorexant Featured | ACT-541468 is a dual orexin receptor antagonist. |
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| DC8191 | Sparsentan(PS433540) Featured | Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively[1]. |
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| DC10417 | Acumapimod (BCT197) Featured | Acumapimod (BCT197) is an orally active p38 MAP kinase inhibitor, with an IC50 of less than 1 μM for p38α. |
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| DC20235 | Ac-WEHD-pNA Featured | Ac-WEAD-pNA is a colorimetric substrate for caspase-1 and caspase-4. |
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| DC22659 | ACY-775 | ACY-775 (ACY775) is a potent and specific HDAC6 inhibitor (IC50=7.5 nM) with improved brain bioavailability. |
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| DC11008 | ACY-957 | ACY-957 (ACY957) is a potent, selective inhibitor of HDAC1 and HDAC2 with IC50 of 7 and 18 nM, shows limited activity against HDAC3 (IC50=1,300 nM) and no activity against HDAC4/5/6/7/8/9 (IC50>20 nM). |
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| DCAPI1273 | Acyclovir (Aciclovir) | Acyclovir (Aciclovir) |
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| DC11754 | AD 2900 Featured | AD 2900 (AD2900, AD-2900) is a novel potent, broad S1P receptor antagonist with IC50 of 3.8, 3.2, 6.2, 5.9 and 0.405 uM for S1P1, 2, 3, 4 and 5 respectively. |
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| DC10633 | AD80 Featured | AD80, a multikinase inhibitor, shows strong activity against human RET, BRAF, S6K, and SRC but were much less active than either AD57 or AD58 against mTOR. The IC50 value for RET is 4 nM. |
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| DC20301 | ADAMTS-5 inhibitor 15f | ADAMTS-5 inhibitor 15f is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
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| DC20302 | ADAMTS-5 inhibitor 8 | ADAMTS-5 inhibitor 8 is a highly potent and selective inhibitor of metalloprotease ADAMTS-5 with IC50 of 30 nM, >50-fold selectivity against ADAMTS-4 and >1000-fold selectivity against ADAMTS-1/13, MMP-13 and TACE. |
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| DC9362 | Adarotene | Adarotene (ST1926) is an effective apoptosis inducer and surprisingly produced DNA damage.ST1926 exhibites a potent antiproliferative activity on a large panel of human tumor cells. IC50 value: 0.12 uM (LNCaP cell) [1] Target: Apoptosis inducer; Antican |
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| DC20642 | ADC-3680 | ADC-3680 (PTR-36, ADC-3680B) is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
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| DC21294 | MK-1029 | ADC-3680 is a potent, selective prostaglandin D2 receptor (DP2, CRTH2) antagonist for the treatment of asthma.. |
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| DC4155 | Adefovir Dipivoxil Featured | Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. |
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| DC10244 | Ademetionine disulfate tosylate | Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. |
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| DC20163 | Adenosine 5'-monophosphate monohydrate; 5'-Adenylic acid;5'-AMP | Adenosine 5'-monophosphate monohydrate (5'-AMP) is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK). |
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| DC20303 | Adhesamine | Adhesamine is a diaryldispirotripiperazine derivative that selectively targets cell-surface glycosaminoglycans, especially heparan sulfate, for increasing cell adhesion and growth. |
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| DC12091 | AdipoRon hydrochloride Featured | AdipoRon hydrochloride is an orally active and specific AdipoR agonist, binding to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM, respectively. |
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| DC7050 | ADL5859 HCl Featured | ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.ADL5859 displays weak inhibitory activity at the hERG channel with an IC50 of 78 μM. The EC50 of ADL5859 against δ opioid |
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| DC20644 | ADM 12 | ADM 12 (ADM_12. |
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| DC9324 | Adoprazine | Adoprazine, a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties. |
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