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Cat. No. Product Name Field of Application Chemical Structure
DC34738 SMPB Crosslinker SMPB crosslinker, or N-Succinimidyl 4-[4-maleimidophenyl]butyrate, is a heterobifunctional protein crosslinking reagent that is reactive toward sulfhydryl and amino groups. SMPB crosslinker's spacer arm is non cleavable. The SMPB protein crosslinker is an extended chain length analog of MBS crosslinker.
DC34739 SMPH Crosslinker SMPH Crosslinker, or Succinimidyl-6-[?-maleimidopropionamido]hexanoate is a water insoluble, heterobifunctional protein crosslinker with a non-cleavable spacer arm length of 14.3 angstroms. The SMPH crosslinking reagent is useful for making antibody drug conjugates (ADCs).
DC34740 Sulfo-LC-SPDP Crosslinker Sulfo-LC-SPDP Crosslinker, or Sulfosuccinimidyl 6-(3'-[2-pyridyldithio]-propionamido)hexanoate, is a cleavable, water soluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The "long chain" Sulfo-LC-SPDP crosslinking reagent has a 15.7 angstrom spacer arm, and is the water soluble analog of LC-SPDP crosslinker.
DC34741 Sulfo-MBS Crosslinker Sulfo-MBS Crosslinker, also known as m-Maleimidobenzoyl-N-hydroxysulfosuccinimide ester, is a non-cleavable, water soluble, heterobifunctional protein crosslinking reagent that is commonly used to crosslink haptens to carrier proteins and enzymes to antibody.
DC34742 Sulfo-SANPAH Crosslinker Sulfo-SANPAH Crosslinker, or N-Sulfosuccinimidyl-6-[4'-azido-2'-nitrophenylamino] hexanoate is a water soluble, heterobifunctional protein crosslinker with a spacer arm length of 18.2 angstroms.
DC34743 Sulfo-SMCC Crosslinker sodium salt Sulfo-SMCC Crosslinker, or Sulfosuccinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a water soluble, heterobifunctional crosslinker. The non-membrane piercing Sulfo-SMCC protein crosslinking reagent can conjugate extracellular proteins. Sulfo-SMCC crosslinker has an 8.3 angstrom, non-cleavable spacer arm.
DC34744 BS2G Crosslinker BS2G Crosslinker, or Bis[Sulfosuccinimidyl] glutarate), is an amine-reactive, water soluble, homobifunctional protein crosslinker. The BS2G protein crosslinker's 5-atom (7.7 angstrom) spacer arm is non-cleavable and the molecule is not cell membrane permeable. The BS2G crosslinking reagent can be used to label cell surface proteins.
DC34745 BS3 Crosslinker BS3 Crosslinker, or Bis[sulfosuccinimidyl] suberate, is an amine-reactive, water soluble, homobifunctional protein crosslinker. The 8-atom spacer arm of the BS3 crosslinking reagent is non-cleavable and the molecule is not cell membrane permeable. The BS3 protein crosslinker can be used to prepare antibody-protein conjugates, for crosslinking cell surface proteins, and for covalently orienting antibody to an immobilized Protein A or Protein G resin.
DC34746 DSG Crosslinker DSG Crosslinker, or Disuccinimidyl glutarate, is a homobifunctional crosslinking reagent that is membrane permeable. DSG protein crosslinker is often used in ChIP assays to determine DNA-protein binding interactions.
DC34747 DSP Crosslinker DSP Crosslinker, also known as DTSSP Crosslinker, is a homobifunctional and cleavable crosslinker that is cell membrane permeable. DSP crosslinker has amine-reactive N-hydroxysuccinimide (NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm, and DSP cross links occur via these NHS esters.
DC34748 DSS Crosslinker DSS crosslinker, or Disuccinimidyl suberate, is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins. DSS crosslinker can be used to conjugate or crosslink intracellular proteins.
DC34749 DSSeb Crosslinker DSSeb Crosslinker, or Disuccinimidyl sebacate, is a homobifunctional crosslinking reagent which is cell membrane permeable. DSSeb Crosslinker is useful in protein crosslinking and making antibody drug conjugates (ADCs).
DC34750 DST Crosslinker DST Crosslinker, or Disuccinimidyl tartrate, is a homobifunctional, cleavable crosslinking reagent (cleavable by oxidizing reagents). DST crosslinker is an excellent choice for applications in which crosslink cleavability is desired without disturbing protein disulfide bonds with reducing reagents.
DC34751 DTSSP Crosslinker Featured DTSSP Crosslinker, or 3,3′-Dithiobis[sulfosuccinimidylpropionate], is a homobifunctional protein crosslinker that is cell membrane impermeable. DTSSP crosslinker can be used to crosslink extracellular and membrane proteins.
DC34752 EGS Crosslinker EGS Crosslinker, or Ethylene glycol bis(succinimidylsuccinate), is a water insoluble homobifunctional crosslinker that can be used to label intracellular proteins. EGS crosslinker is often used in ChIP assays to determine DNA-protein binding interactions.
DC34753 Sulfo-EGS Crosslinker Sulfo-EGS Crosslinker, or Ethylene glycol bis(sulfosuccinimidylsuccinate), is a water soluble homobifunctional crosslinker. Sulfo-EGS Crosslinker can be used to label cell surface proteins as the molecule is not cell membrane permeable.
DC34754 CDI Crosslinker CDI Crosslinker, or N,N'-Carbonyldiimidazole, is a zero-length crosslinker that is often employed in the coupling of amino acids for peptide synthesis and also in organic synthesis. CDI can be used to convert alcohols and amines into carbamates, esters, and ureas.
DC34755 DCC Crosslinker DCC Crosslinker, N,N'-dicyclohexylcarbodiimide, is a zero-length crosslinker that is often employed in peptide synthesis and organic synthesis. DCC's carbodiimide is useful for coupling amines and carboxylates without the insertion of spacer atoms. DCC crosslinker is commonly used in the synthesis of active ester-containing reagents.
DC34756 EDC-HCl Crosslinker EDC-HCl Crosslinker is a zero-length crosslinker that can be used to conjugate carboxyl functional groups to primary amines. It is ideal for covalently binding proteins or peptides to carboxyl containing beads, resins, or other nanoparticals.
DC34757 BS3-d4 BS3-d4 Deuterated Crosslinker, or Bis(Sulfosuccinimidyl) 2,2,7,7-suberate-d4, is a water soluble and membrane impermeable, protein crosslinking agent with four deuterium atoms to provide a four dalton shift by mass spectrometry.
DC34758 DSG-d4 Deuterated Crosslinker DSG-d4 Deuterated Crosslinker, or Bis[Succinimidyl] 2,2,4,4-glutarate-d4, is a cell membrane permeable, protein crosslinker containing four deuterium atoms to provide a four dalton shift by mass spec analysis.
DC34759 DSS-d4 Deuterated Crosslinker DSS-d4 Deuterated Crosslinker, or Bis[Succinimidyl] 2,2,7,7-suberate-d4 is a cell membrane permeable crosslinking agent with 4 deuterium atoms that provide a 4 dalton shift by mass spectrometry analysis.
DC34760 NHS-Biotin NHS-Biotin, Succinimidobiotin, is a primary amine reactive biotinylation reagent used in Biotin-Streptavidin binding reactions. The NHS-Biotin molecule is cell membrane permeable and can be used to covalently label intracellular proteins.
DC34761 NHS-LC-Biotin NHS-LC-Biotin, or Succinimidyl 6-(biotinamido)hexanoate, is an amino-reactive biotinylation reagent with a long spacer arm which helps alleviate steric hindrance. NHS-LC-Biotin is used to biotinylate proteins, peptides, or amino acids by reacting with primary amines as found in the N-terminus and Lysine side chains.
DC34762 NHS-SS-Biotin NHS-SS-Biotin, or Succinimidyl-2-(biotinamido)-ethyl-1,3'-dithiopropionate, is an amine-reactive biotinylation reagent that is cleavable when the disulfide (-S-S-) bond is reduced. The resulting biotinylated protein can then be detected when used in conjunction with streptavidin. Therefore, NHS-SS-Biotin can be useful in antibody purification.
DC34763 Sulfo-NHS-Biotin Sulfo-NHS-Biotin, or Sulfosuccinimidyl biotin, is a water soluble biotinylation reagent used in Biotin-Streptavidin binding reactions. It is ideal for biotinylating antibody or protein that can then be used for protein detection or immobilization when used in conjunction with streptavidin and Immobilized Streptavidin. Sulfo-NHS-Biotin is particularly useful for targeting cell surface proteins in Streptavidin-Biotin assays.
DC34764 Sulfo-NHS-LC-Biotin Sulfo-NHS-LC-Biotin, or Sulfosuccinimidyl 6-(biotinamido) Hexanoate, is a long chain, water soluble biotinylation reagent that is reactive toward primary amine groups. Similar to Sulfo-NHS-Biotin, Sulfo-NHS-LC-Biotin is designed to target cell surface proteins.
DC34765 Biotin-HPDP Biotin-HPDP, also known as N-[6-(Biotinamido)hexyl]-3’-(2’-pyridyldithio)-propionamide, is a sulfhydryl reactive biotinylation reagent with a long chain, cleavable spacer arm.
DC34766 Iodoacetyl-LC-Biotin Iodoacetyl-LC-Biotin, or N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediamine, reacts with sulfhydryl groups to form stable thioether linkages.
DC34767 Biotin Hydrazide Biotin Hydrazide, or Biotin-Hz, is a carbohydrate reactive biotinylation reagent. Biotin Hydrazide is a great choice for labeling mouse monoclonal antibodies, lectins, sugars, unpaired cytosine residues in nucleic acids, and glycoprotiens.

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