Synephrine (R-isomer), also known as (-)-Synephrine, inhibits eotaxin-1 expression via the STAT6 signaling pathway.

Tenuazonic acid is a metabolite found in a strain of the fungus Alternaria tenuis Auct. which functions as an antibiotic with antiviral and antineoplastic properties, and may also act as a mycotoxin.

Clindamycin is an antibacterial agent that is a semisynthetic analog of LINCOMYCIN.

Pirlimycin Hydrochloride is a semi-synthetic lincosaminide antibiotic. Pirlimycin Hydrochloride is a Clindamycin analog.

Proctolin modulates interneuronal and neuromuscular synaptic transmission in a wide variety of arthropods.

Spinorphin is a heptapeptide which is a potent inhibitor of enkephalin-degrading enzymes from the spinal cord or brain; does not show inhibitory activity toward enkephalin-degrading enzymes from kidney or blood; member of the opioid hemorphin family.

Vapreotide is used in therapy of experimental pancreatic neoplasms in hamsters.

PD-173212 is a small molecule N-type calcium channel blocker.

trans-Clovamide is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.). It has antioxidant and antiradical properties and has shown neuroprotective effects (EC50s = 0.9-3.7 μM) in several in vitro models of neuronal death.

Tirofiban HCl is a platelet glycoprotein-IIb/IIIa receptor antagonist.

N-Benzoyltyrosine is a peptide.

Glycyltyrosine is a dipeptide composed of glycine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.

Tyrosyltyrosine is a peptide.

Antipain is an oligopeptide produced by various bacteria which acts as a protease inhibitor.

BPC 157 is a 15-amino acid fragment of a gastric peptide, BPC, with hepatoprotective effects.

Ureidovaline is an intermediate in the synthesis of Ritonavir.

PD-166793 is a cell-permeable biphenylsulfonylvaline compound that acts as a potent inhibitor against MMP-2, -3, and -13 (IC50 = 47, 12, and 8 nM, respectively) and a weaker inhibitor against AMP deaminase (20% inhibition at 0.1 μM), MMP-1, -7, -9, and -14 (IC50 = 6.1, 7.2, 7.9, and 0.24 μM, respectively). Shown to offer therapeutic benefits in vivo in various animal models of heart failure and diabetes.

Fructosylvaline is an Amadori compound having the potential to alter cellular adhesion, inhibit cancer metastasis and induce apoptosis.

Valsartan benzyl ester is a Valsartan intermediate.

Valacyclovir Related Compound D is a bioactive chemical.

Vasicinone is a quinazoline alkaloid that can be isolated from A. vasica leaves and demonstrates bronchodilatory activity. It also is reported to possess antioxidant activity in nitric oxide and ABTS radical scavenging assays.

Vasicine is an alkaloid.

Efavirenz, (R)- is a nonnucleoside HIV-1 reverse transcriptase inhibitor. Efavirenz, (R)- is an antiviral.

Butalamine is a vasodilator (peripheral) with local anesthetic effects. Butalamine has been shown to inhibit state 3 respiration and decrease ADP/O in rat liver.

Dequalinium chloride is a topical bacteriostat that is available as various salts. It is used in wound dressings and mouth infections and may also have antifungal action, but may cause skin ulceration.

(Z)-Abienol is a bicyclic diterpene, and is the major labdanoid present in some oriental tobacco cultivars, where it constitutes a precursor of important flavours and aromas.

Labetalol is a mixed alpha/beta adrenergic antagonist that is used to treat high blood pressure. It can be given intravenously in severe hypertensive situations, or by mouth for long term hypertension management. Studies suggest that the pharmacokinetics of labetalol are significantly affected by the common CYP2C19 polymorphisms.

Fenpropimorph is a small moluecule fungicide.

Hydrocortisone butyrate is a topical corticosteroid use to treat a variety of dermatological conditions. It acts as an antiinflammatory, antiproliferative and immunosuppresive agent.

Benoxinate HCl is a local anesthetic used in ophthalmology to numb the surface of the eye for a variety of procedures.

Carbetamide is a mitosis inhibitor.

Magnesium lactate is a buffering agent and magnesium donor

Lactamide is used in 2M solution as hyperosmotic agent on ciliary epithelium.

Lactitol is a gastrointestinal agent.

Maclurin is isolated from Maclura pomifera. Maclurin is composed of two isoforms (isolectins); some sequence similarity to jacalin; potent non-specific blood-group hemagglutinin.

Lamivudine sulfoxide, (R)- is a metabolite of Lamivudine; a potent nucleoside reverse transcriptase inhibitor and antiviral agent. Lamivudine has been used for treatment of chronic hepatitis B.

Lamivudine impurity A RS is a bioactive chemical.

Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents.

Anazolene sodium is a diagnostic Aid (Blood Volume and Cardiac Output Determination).

Digitoxin is a cardiac glycoside sometimes used in place of DIGOXIN. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.

Digoxigenin is a cardenolide which is the aglycon of digoxin. Can be obtained by hydrolysis of digoxin or from Digitalis orientalis L. and Digitalis lanata Ehrh.

Purpurea glycoside B is a cardiac glycoside.

Purpurea glycoside A is a cardiac glycoside analog.

Cloethocarb is a molluscicide.

Alginic acid is a suitable reagent used to study the in-vitro and in-vivo mitogenic activity of alginates. It is suitable for use in the spectrophotometric determination of transparent exopolymer particles by dye-binding assay.

Fluometuron is an herbicide. In the United States it was approved for use on cotton and sugarcane crops in 1974, but since 1986 is only approved for use on cotton.

Kaolin is the most common mineral of a group of hydrated aluminum silicates.It is prepared for pharmaceutical and medicinal purposes by levigating with water to remove sand, etc. The name is derived from Kao-ling (Chinese: "high ridge").

Metildigoxin is a semisynthetic digitalis glycoside with the general properties of DIGOXIN but more rapid onset of action. Its cardiotonic action is prolonged by its demethylation to DIGOXIN in the liver. It has been used in the treatment of congestive heart failure.

Dibutyltin dilaurate is used in prevention of parasitic dieases in cattle and sheep.

Methomyl is a carbamate insecticide with anticholinesterase activity.

Lanoconazole is a topical antifungal agent.

Lanosterol is a triterpene that derives from the chair-boat-chair-boat folding of 2,3-oxidosqualene. It is metabolized to CHOLESTEROL and CUCURBITACINS. Lanosterol is a naturally-occurring sterol and biosynthetic precursor of several animal, fungal, and protozoan steroids, including cholesterol and ergosterol. Defects in the processing of lanosterol contribute to a wide variety of disorders, including the formation of cataracts. Similarly, certain fungicides act by blocking lanosterol processing by fungi.

Lanostenol is a derivative of Lanosterol. It is also one of cytochrome P 450 lanosterol 14α-demethylase , which is shown to have an important role in regulating meiosis and reproduction.

Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. It is also occasionally used for amebiasis that is occurring outside the intestines, rheumatoid arthritis, and lupus erythematosus. Chloroquine enters the red blood cell, inhibiting the parasite cell and digestive vacuole by simple diffusion. Chloroquine then becomes protonated (to CQ2+), as the digestive vacuole is known to be acidic (pH 4.7); chloroquine then cannot leave by diffusion. Chloroquine caps hemozoin molecules to prevent further biocrystallization of heme, thus leading to heme buildup.

Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.

M 12325 is used in the manufacture of furosemide; occupational asthma and rhinitis was observed in workers from a lasamide production line.

Alachlor is a herbicide and pesticide.

Cycloxydim is a cyclohexene oxime herbicide that is used for the control of grass weeds of many agricultural and horticultural broad-leaved crops.

Pinaverium bromide is a spasmolytic agent with low incidence of anticholinergic effects. Antispasmodic.

Lateritin is An Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor and a platelet aggregation inhibitor isolated from the mycelial cake of Gibberella lateritium; bassiatin is the (3S,6R) isomer.

Silthiofam is very effective against Ggt, and recently it has been widely used for the control of take-all in China. Gaeumannomyces graminis var. tritici (Ggt) causes Wheat take-all.

Latrepirdine is an orally-available drug, approved in Russia for use as a non-selective antihistamine, that has shown promise in the treatment of neurodegenerative diseases, including Alzheimer’s and Huntington’s disease. In addition to reported activity in preventing the onset and progression of disease by being neuroprotective, dimebolin appears to promote clinical improvement by increasing cognitive function. At the cellular level, dimebolin appears to have diverse effects, inhibiting the neurotoxic action of β-amyloid and blocking L-type calcium channels,5 inhibiting NMDA-type glutamate receptors, and preventing mitochondrial leakage.

Laudanosine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium.

Benzododecinium chloride is an eye irritant.

LAPAO is a bioactive chemical.

Laurdan is a fluorescent marker.

Lauroyl peroxide is an oxidizing agent. Can ignite organic materials; hence a dangerous fire and explosion risk. Strongly reduced material such as sulfides, nitrides, and hydrides may react explosively. Vigorous reactions with other reducing agents.

Erythromycin estolate is a macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.

Lauryl gallate is the ester of dodecanol and gallic acid. As a food additive it is used under the E number E312 as an antioxidant and preservative.

Dodecyl maltoside is a surfactant.

Dodine is a fungicide used to control scab on apples, pears and pecans, brown rot of peaches, and several foliar diseases of cherries, strawberries, peaches, sycamore trees and black walnuts. It is also used as an industrial biocide and preservative. It is available as soluble concentrate and wettable powder formulations.

Thionin chloride is a coloring agent.

Fenazaflor is used as an acaricide and insecticide.

Lawesson's reagent is a thiation agent.

Erythrosine sodium (close form) is a tetraiodofluorescein used as a red coloring in some foods (cherries, fish), as a disclosure of DENTAL PLAQUE, and as a stain of some cell types. It has structural similarity to THYROXINE.

Pantethine is a derivative of vitamin B5.

LD 490 is a laser dye.

LD-473 is a laser dye.

Cinnamtannin B1 is an A-type proanthocyanidin contained in several plant species such as Laurus nobilis L., Vaccinium vitis-idaea, Parameria laevigata, Cinnamomum zeylanicum and Lindera umbellata. Cinnamtannin B-1 is a potent antioxidant and protective agent against oxidative stress and apoptosis in human platelets. Cinnamtannin B-1 is a Cox-2 (cyclooxygenase-2) inhibitor.

Isofenphos is a pesticide residue found in plant based food that may have acute health risks for consumers.

Lead phthalocyanine is a selective carrier for preparation of a cysteine-selective electrode.

Lead salicylate is a combustion chemical.

Bentazone has been used as analytical standard in liquid chromatograph with a photodiode array (PDA) detector coupled in series with a mass spectroscopy (MS) detector equipped with an atmospheric pressure electrospray ionization source (ESI) for the determination of bentazon and its transformation products.

Fenthion is a potent cholinesterase inhibitor used as an insecticide and acaricide.

Lauramidopropyl betaine is a surface active substance.

Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens. It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively). Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 μg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties.

Quinoxyfen is a fungicide of the phenoxyquinoline class used to control powdery mildew, Uncinula necator (Schw.) Burr.

Penicillin G benzathine anhydrous is a semisynthetic antibiotic prepared by combining the sodium salt of penicillin G with N,N'-dibenzylethylenediamine.

Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma.

Lenperone is an antipsychotic of the butyrophenone class; like other major tranquilizers, it has some alpha-adrenergic blocking action & is antiemetic.

Pyridate is a herbicide.

Leptophos oxon is a phosvel analog-oxygen substituting sulfur.

Fenaminosulf is an active ingredient in several commercial fungicides, and reported to be mutagenic in Salmonella typhimurium.

TEPP is a topical agent for glaucoma.

Letrozole related compound B is an aromatase inhibitor impurity.

Kemptide is a heptapeptide used as substrate for cAMP dependent protein kinase.

CC 1014 isiIsolated from Penicillium lilacinum. CC 1014 is a polypeptide antibiotic that inhibit phosphorylation of ADP, Mg ATPase.

Diacetyldichlorofluorescein is the stable storage form of dichlorofluorescein.

Leucogentian violet is a cationic triarylmethane dye. LCV is a reduced form of gentian violet (crystal violet) and thus, it is colorless. It has an affinity for both cellulosic and proteinaceous materials. LCV and hydrogen peroxide react with the hemoglobin in blood and turn the blood impression to purple/violet color. Therefore, the dye is widely used to stain blood residue on both porous and non-porous materials.

Leucokinin I is an eight amino acid neuropeptide found in the nervous system of the bowfly. Also isolated from head of Madeira cockroach Leucophaea maderae

Leucomycin a5 is a metabolite from the leucomycin complex, which was originally isolated from S. kitasatoensis. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.04-0.8 μg/ml) but not against K. pneumoniae, S. typhimurium, or E. coli with MICs ranging from 5 to >10 μg/ml. Leucomycin A5 is also active against penicillin-susceptible and -resistant S. pyogenes (MICs = 0.8 and 3.2 μg/ml, respectively) and S. faecalis (MIC = 0.8 μg/ml).

Spiramycin III is an antibiotic chemical within the erythromycin/carbomycin group of compounds.

Leucyltyrosine is a peptide.

Daunomycinone (NSC-109351) is a metabolite of daunomycin. Daunomycin is an antibiotic with antitumor activity.

MCPA is a powerful herbicide used as a selective weed killer.

Leupeptin is a protease inhibitor, will strongly inhibit Trypsin, Papain, Plasmin, Thrombokinase, Kallikrein and Cathepsin B. The half-maximal inhibitory concentration ranges from 0.5 to 75 μg/ml, depending on the enzyme and the substrate. Leupeptin does not inhibit Chymotrypsin, Elastase, Renin, or Pepsin.

Vinformide is a potent cytostatic agent.

BIIK-0277 is a β2-adrenoceptor agonist. Bronchodilator; tocolytic. Levalbuterol USP Related Compound E.

Vardenafil, also known as BAY 38-9456, is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil. Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's.

Chloramphenicol base is a bioactive chemical.

Levolansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K±stimulated ATPase pumps in parietal cells (IC50 = 5.2 μM), inhibiting gastric acid secretion and increasing intragastric pH. It also inhibits acid formation in isolated canine parietal cells (IC50 = 82 μM). Lansoprazole is an enantiomerically pure form of lansoprazole. Both (S)- and (R)-lansoprazole are pharmacologically active with similar potencies.

Candicidin is a mixture of antifungal heptaene macrolides from Streptomyces griseus or Actinomyces levoris used topically in candidiasis. The antibiotic complex is composed of candicidins A, B, C, and D, of which D is the major component.

N-Acetylthyroxine is a Thyroxine analogue, a thyroid hormone for use in diagnosing and treating diabetes.

Dimethylaminopropyl lauramide is a skin sensitizer.

Metribuzin is a triazine herbicide.

Lexithromycin is a semi-synthetic antibiotic derived from erythromycin. Lexithromycin has improved absorption in vivo over erythromycin due to increased hydrophopicity and pH stability. As with other macrolides, lexithromycin prevents protein synthesis by binding the ribosome at the polypeptide exit tunnel. Formulations containing lexithromycin were tested in clinical trials as treatment for HIV but were discontinued.

Propineb is used as a fungicide.

(R)-Licarbazepine Acetate is a promising antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.

Lignocaine N-oxide is a novel metabolite of Lidocaine, an anesthetic and antiarrhythmic agent.

Mesoridazine, also know as thioridazine EP impurity B is a phenothiazine antipsychotic with effects similar to CHLORPROMAZINE.

Levophacetoperan HCl is a sympathomimetic central nervous system stimulant and is commonly used to treat depression. Levophacetoperane is also a known analeptic and is strongly linked to apnea reversal in dogs after a single intravenous injection.

Prednisolone valerate acetate is a derivative of Prednisolone, which is a synthetic corticosteroid, metabolically interconvertible with prednisone, and an impurity of Hydrocortisone. Prednisolone 21-Acetate Valerate is used in multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.

Pyrithioxine HCl is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.

Cryptating agent 222 forms ligands with metal cations. It is a cryptand used with potassium mirror to reduce a hindered distannene to a crystalline radical anion.

Ligustilide A is an active ingredient isolated from the medicinal plants Cnidium officinale and Angelica acutiloba. Ligustilide A inhibits benzo(a)pyrene-induced CYP1A1 upregulation in cultured human keratinocytes via ROS-dependent Nrf2 activation.

Chlormequat chloride is a plant growth regulator that is commonly used on ornamental plants.

Lilial is a high-tonnage perfumery ingredient with a lily-of-the-valley odour, which is a CMR2 material.

Cefalonium (anhydrous) is a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows.

Calcium lignosulfonate is a granulating agent for limestone and ores, compaction aid for coal and metal wastes, and dispersing agent for gypsum and clay slurries.

Dexamethasone palmitate is a liposteroid for treatment of hemophagocytic lymphohistiocytosis.

2,4-D-butyl is a bioactive chemical.

Benzidine orange exhibits mutagenic and carcinogenic activity.

Glyceryl monolinoleate inactivates or inhibits African Swine Fever virus.

Betamethasone sodium phosphate is a Betamethasone derivative. It is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.

Dienestrol diacetate is a derivative of the synthetic non-steroid phenolic compound, DIENESTROL, which exhibits estrogenic activities.

Lipoamide is an Indirect Antioxidant.

Lipofundin S is an emulsion containing soy bean oil, soy phosphatides & glycerol.

Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.

Sorbitan monostearate is an ester of sorbitan (a sorbitol derivative) and stearic acid and is sometimes referred to as a synthetic wax.

Fentin acetate is an organotin compound. Triphenyltin Acetate much like its hydroxide analogue is used as a fungicide and antifeeding compound for insect control. Recent studies show that Triphenyltin Acetate may have adverse effects on the reproductive and immune systems and may disrupt the endocrine system.

Malaoxon, also known as Malathion impurity B, is an insecticide.

Difenoxuron is a herbicide.

Lissamine rhodamine B is a new Radiotracer for Imaging Tumors by Positron Emission Tomography.

Lissamine rhodamine B sulfonyl chloride is a fluorescent protein label forming stable conjugates.

Lithium guanosine triphosphate functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. GTP activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation, and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle formation. In addition to its role in signal transduction, GTP also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

Glycolithocholic acid is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.

Lithium octadecanoate is a soap.

Edoxaban (INN, codenamed DU-176b, trade name Lixiana) is a potent, selective factor Xa inhibitor, which has good oral bioavailability. Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor. It is being developed by Daiichi Sankyo. It was approved in July 2011 in Japan for prevention of venous thromboembolisms (VTE) following lower-limb orthopedic surgery. It was also approved by the FDA in January 2015 for the prevention of stroke and non?–central-nervous-system systemic embolism.

Ilicicolin C is a natural antibiotic derived from fungal source.

Nadoxolol HCl is a beta-adrenergic receptor blocker.

Acetylaszonalenin is a fungal metabolite that has been found in A. flavipes.1 It acts as an antagonist of neurokinin-1 (NK1) receptors, inhibiting binding of substance P with a Ki value of 170 μM.

Fluindione is a hematologic agent.

Cantabiline sodium is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in analytical chemistry for the determination of NITRIC ACID.

Racemethionine is a preparation of METHIONINE that includes a mixture of D-methionine and L-methionine isomers.

Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg/ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the human recombinant enzyme) and production of 12(S)-HETE (Item No. 34570) by 12(S)-lipoxygenase (IC50 = 28.5 μM). In vivo, lobaric acid (250 μM) decreases lesion number, but not lesion diameter, in tobacco leaves infected with tobacco mosaic virus (TMV).

Lobenzarit sodium is an antirheumatic agent.

Harman is a beta-carboline.

Flumethasone pivalate is a topical difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. A prompt decrease in inflammation, exudation and itching is experienced after application. It is used to study adrenocortical suppression, plasma transcortin binding, and cutaneous atrophy and telangiectasia.

Lodenafil carbonate is a new PDE-5 inhibitor used for oral therapy in erectile dysfunction.

Norethindrone acetate is used in combination with estrogen as a contraceptive (oral). It is reasonably anticipated to be a human carcinogen.

Lofexidine reduces narcotic withdrawal symptoms.

Bensulfuron-methyl is a herbicide.

Etebenecid is a uricosuric drug.

X 14868A, also known as Maduramicin, is a natural polyether ionophore antibiotic first isolated from the actinomycete Actinomadura rubra. It is cytotoxic against Cryptosporidium spp. and is commonly used in veterinary medicine as an anti-coccidial agent. Maduramicin is also cytotoxic against Plasmodium gametocytes and potentiates the gametocytocidal activity of the pyrazoleamide PA21A050.

Loratadine specified impurity F is a fluorinated analog of Loratadine, which is a nonsedating-type histamine H1-receptor.

4-Chloroloratadine is an impurity of Loratadine.

Isoloratadine is a Loratadine impurity. An isomer of Loratadine used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.

Omeprazole sodium is the salt analogue of Omeprazole, which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.

Trityllosartan is an intermediate in the preparation of Losartan impurities.

Lotaustralin is a cyanogenic glycoside.

Cyanox CY 1790 is an antioxidant.

Boldine is an alkaloid of the aporphine class that can be found in the boldo tree and in Lindera aggregata. Boldine has antioxidant activity that effectively protects against free radical induced lipid peroxidation or enzyme inactivation. In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have hepatoprotective, cytoprotective, antipyretic and anti-inflammatory effects.

Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum. It is an irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Pure capsaicin is a volatile, hydrophobic, colorless, odorless, crystalline to waxy compound.

PYR-9588, CAS#2199-58-8, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs.

PYR-4897, CAS#60024-89-7, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs.

TPY-5628, CAS#149365-62-8, is a useful intermediate for chemical synthesis of a number of biologically important molecules, including porphyrins, bile pigments, photosensitizers, anticancer drugs.

DBB-0920, CAS#4440-92-0, is a dibenzene-butanedione derivative nad a useful intermediate for chemical synthesis of terameprocol and a number of biologically important molecules.

DBF-6339, CAS#4676-33-9, is a dibenzene-furan derivative and a useful intermediate for chemical synthesis of a number of biologically important molecules, including anticancer drugs.

Octaethylporphyrin, CAS#2683-82-1, is a stable and useful porphyrin compound for research use.

VWN38241, also known as BPD-A-1,4-diene , and benzoporphyrin derivative Ring A -1,4-diene, is an important precursor for making PDT drug verteporfin. Verteporfin (trade name Visudyne), a benzoporphyrin derivative, is a medication used as a photosensitizer for photodynamic therapy to eliminate the abnormal blood vessels in the eye associated with conditions such as the wet form of macular degeneration. VWN38241 has CAS#94238-24-1 and inchi key VTMVQLSZTQAYOV-WKGWVRGVSA-N. For the convenience of scientific communication, tt is named as VWN38241 according to Hodoodo Chemical Nomenclature.

SSN38434, also known as BPD-B-1,4-diene and Benzoporphyrin Ring B 1,4-diene, is a product from the synthesis of verteporfin. BPD-B-1,4-diene may be useful for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic (PDT) drugs. SSN38434 has CAS#94238-43-4. For the convenience of scientific communication, It is named as SSN38434 according to Hodoodo Chemical Nomenclature. Synthesis of SSN38434 was reported in J. org. Chem 1986, 51(7):1094-100. Note: SSN38434 was previously name as OZN38434.

LZN86178, also known as BPD-Ring B and benzoporphyrin Ring B derivative, is a product from the synthesis of verteporfinin. BPD-Ring B may be useful for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic (PDT) drugs. LZN86178 has CAS#143986-17-8. For the convenience of scientific communication, tt is named as LZN86178 according to Hodoodo Chemical Nomenclature.

DBB-7373, CAS#36287-37-3, is a Dibenzene-butandione derivative. DBB-7373 is a useful intermediate for synthesis of teremeprocol and other bioactive chemicals and drugs.

6-Chloro-1-tetralone is an important intermediate for the synthesis of pharmaceutical compounds.

SMCC, also known as succinimidyl-4-[N-maleimidomethyl]cyclohexane-1-carboxylate, is a heterobifunctional protein crosslinker. SMCC is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length cyclohexane-stabilized spacer arm (8.3 angstroms). SMCC conjugation occurs via a maleimide group that is sulfhydryl (thiol; -SH) reactive and a NHS ester group that is amine reactive and forms stable, covalent protein crosslinks.

Paclitaxel-Succinic acid, also known as Paclitaxel Succinate or Paclitaxel-hemisuccinic acid, is a paclitaxel derivative with a succinic acid linker. The carboxy group of Paclitaxel-Succinic acid, after activiating, can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-Succinic acid is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research.

Paclitaxel-MVCP, also known as MC-Val-Cit-PAB-Paclitaxel, is a paclitaxel derivative with a MC-Val-Cit-PAB linker. Mc-Val-Cit-PAB is a cathepsin cleavable ADC peptide linker. Paclitaxel-MVCP can be used to conjugate with other molecules such as peptides, proteins, antibodies or enzymes, or polymers. Paclitaxel-MVCP is a useful agent to make Paclitaxel-conjugate for drug delivery, nanodrug research.

WZ4002-hydroxy is a WZ4002 (MedKoo Cat#: 203170) derivative or WZ4002 analog. In which the methoxy group is replaced by hydroxy group. WZ4002 is EGFR inhibitor against EGFR T790M (mutation of the gatekeeper T790 residue) which is detected in 50% of clinically resistant patients to gefitinib or erlotinib. WZ4002 has a basic chemical framework (covalent pyrimidine) which is different from that of other EGFR inhibitors.

WZ8040-hydroxy is a WZ8040 (MedKoo Cat#406574) derivative or analog molecule. Compared to WZ8040, WZ8040-hydroxy has an extra hydroxy group in the benzene ring. WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor with potential anticancer activity. WZ8040 is about 30-fold more potent against EGFR T790M, and up to 100-fold less potent against wild-type EGFR, than other quinazoline-based EGFR inhibitors such as CL-387785 and HKI-272. WZ-8040 may be clinically more effective and better tolerated than quinazoline-based inhibitors.

L-allo-Isoleucine may be used in studies on maple syrup urine disease (MSUD). In patients with classical MSUD (n = 7), alloisoleucine was beyond the cutoff value in 2451 of 2453 unselected samples. In patients with variant MSUD (n = 9), alloisoleucine was >5 micromol/L in all samples taken for establishment of diagnosis and in 94% of the samples taken for treatment control (n = 624). With the other branched-chain amino acids, the frequency of diagnostically significant increases was <45%. The plasma L-alloisoleucine above the cutoff value of 5 micromol/L is the most specific and most sensitive diagnostic marker for all forms of MSUD.

PRP-194, CAS#596085-87-9, has a chemical name 5-chloro-2,3,3-trimethyl-3H-pyrrolo[2,3-b]pyridine, is a useful precursor for chemical synthesis of bioactive molecules and dyes. There is no formal name for this chemical. For the convenience of communication, we temporally called it as PRP-194, in which PRP is originated from PyRrolo[2,3-b]Pyridine, and 194 is originated from its molecule weight 194.

Decyl-TPP, also known as (1-Decyl)triphenylphosphonium bromide, may be used as intermediate for chemical synthesis, Decyl-TPP can be also used as an inactive control or as a reference to mitoquinone (MitoQ).

MDK08445 is an important intermediate or precursor for the synthesis of Cefiderocol. MDK08445 has CAS#1225208-44-5. We assigned a code name as MDK08445 (last 5 digital of its CAS# was used). Cefiderocol, also known as S-649266, is a potent siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. S-649266 shows potent in vitro activity against the non-fermenting Gram-negative bacteria Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia, including MDR strains such as carbapenem-resistant A. baumannii and metallo-β-lactamase-producing P. aeruginosa.

MDK71803 is an important intermediate or precursor for the synthesis of Cefiderocol. MDK71803 has CAS#137171-80-3. We assigned a code name as MDK71803 (last 5 digital of its CAS# was used). Cefiderocol, also known as S-649266, is a potent siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. S-649266 shows potent in vitro activity against the non-fermenting Gram-negative bacteria Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia, including MDR strains such as carbapenem-resistant A. baumannii and metallo-β-lactamase-producing P. aeruginosa.

Biotin-PEG6-Maleimide is a PEG derivative containing a biotin group and a maleimide group for labeling and crosslinking cysteines and other sulfhydryls. The maleimide group reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.

Fmoc-Val-Ala-PAB, also known as Fmoc-Val-Ala-PAB-OH, is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery.

Mc-Val-Ala-PAB is a useful linker to make antibody-drug-conjugate (ADC) for targeting drug delivery.

The chemcial name of CAS# 873436-91-0 is 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine

t-Boc-N-amido-PEG9-amine is a PEG derivative containing an amino group and Boc-protected amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. PEG Linkers are useful in the development of antibody drug conjugates.

(R)-Ofloxacin is a R-isomer of Ofloxacin, which is an antibiotic useful for the treatment of a number of bacterial infections.