| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DCC3697 | Notum-in-23dd | Novel potent inhibitor of notum carboxylesterase activity |
|
| DCC3698 | Notum-in-24 | Novel potent notum inhibitor (OPTS IC50 3.6nM; TCF-LEF EC50 220nM), showing good plasma exposure and reasonable CNS penetration |
|
| DCC3699 | Nov-lrrk2-11 | Novel potent LRRK2 inhibitor |
|
| DCC3700 | Novolactone | Natural inhibitor of the allosteric regulation of Hsp70 |
|
| DCC3701 | Np-005497 | Natural inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana |
|
| DCC3702 | Npa101.3 | Second-Generation RET/VEGFR2 Inhibitor |
|
| DCC3703 | Np-c86 | Novel stabilizer of long noncoding RNA (lncRNA) GAS5, binding to GAS5 with high affinity, and increasing GAS5 levels and glucose uptake in diabetic patient adipocytes |
|
| DCC3704 | Npd-008 | Novel Inhibitor of Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) |
|
| DCC3705 | Npd-039 | Novel Inhibitor of Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) |
|
| DCC3706 | Npd-048 | Novel inhibitor of Trypanosoma brucei PDEB1 (TbrPDEB1) |
|
| DCC3707 | Npd11033 | Novel selective SIRT2 inhibitor, creating a hydrophobic cavity behind the substrate-binding pocket after a conformational change of the Zn-binding small domain of SIRT2 |
|
| DCC3708 | Npd12671 | Novel activator of 15-ADON production, significantly increasing the transcription of Tri6, a transcription factor gene necessary for trichothecene biosynthesis, in both trichothecene-inducing and noninducing culture conditions |
|
| DCC3709 | Npd2639 | Novel biomediator, inducing reveromycin production in Streptomyces sp. SN-593 |
|
| DCC3710 | Npd6689 | Novel tubulin inhibitor |
|
| DCC3711 | Npd7155 | Novel competitive MTH1 inhibitor |
|
| DCC3712 | Npd8617 | Novel tubulin inhibitor |
|
| DCC3713 | Npd9055 | Novel heterotrimeric G-protein Gi modulator, inhibiting GDP/GTP exchange on a Gαi subunit induced by a G-protein-coupled receptor agonist, but not on another G-protein from the Gαs family, regulating Gβγ-dependent cellular processes, most likely by causin |
|
| DCC3714 | Nplc0393 | Novel inhibitor of TGF-β1 signaling pathway, inhibiting the upregulation of MAT2A mechanistically, dose-dependently activating PP2Cα and efficiently alleviating liver fibrosis |
|
| DCC3715 | Npr-c Activator 1 | Novel potent activator of the natriuretic peptide receptor C (NPR-C) with EC 50 ~1 μM |
|
| DCC3716 | Nps-89636 | Calcilytic negative allosteric modulator of calcium-sensing receptor (CaR) |
|
| DCC3717 | Nqo1 Substrate 1 | Novel substrate for NAD(P)H: quinone oxidoreductase 1 (NQO1), acting as an effective intracellular ROS generator for the treatment of drug-resistant non-small-cell lung cancer |
|
| DCC3718 | Nr2b-in-1 | Novel NMDA/NR2B Antagonist |
|
| DCC3719 | Nrf2/ho-1 Activator Ll202 | Novel activator of the Nrf2/HO-1 pathway, upregulating heme oxygenase-1 (HO-1) via promoting nuclear translocation of nuclear factor erythroid 2 (NF-E2)-related factor 2 (Nrf2) to regulate LPS‐induced oxidative stress in macrophages |
|
| DCC3720 | Nrf2-activator Featured | Nrf2-Activator is a potent Nrf-2 activator. |
|
| DCC3721 | Ns-0011 | Novel inhibitor of CDK5 translocation, increasing CDK5 accumulation in the nucleus, suppressing both cancer cell proliferation and xenograft tumorigenesis. |
|
| DCC3722 | Ns-2710 | Potent, non-selective partial agonist at GABAA receptors with little efficacy at the alpha1 subtype and more at alpha2 and alpha3 |
|
| DCC3723 | ns3/4a-in-12 | Novel Inhibitor with Activity against NS3/4A proteases from Multiple Hepatitis C Virus Genotypes |
|
| DCC3724 | ns3-in-5 | Novel allosteric inhibitor of HCV NS3 protein function |
|
| DCC3725 | Ns4591 | Novel molulator of SK-IK channels [small- and intermediate-conductance Ca2(+) -activated K(+) channels] |
|
| DCC3726 | Ns-6740 | Novel potent α7 nAChR partial agonist |
|
