DCC3877 |
Ofh244 |
Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist and weak inverse agonist |
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DCC3878 |
Ofh3911 |
Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist |
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DCC3879 |
Ofh3912 |
Novel highly potent and selective M3 muscarinic acetylcholine receptor antagonist |
|
DCC3880 |
Og488-bapta-1-am |
Cell-permeable, fluorescent Ca2+ indicator |
|
DCC3881 |
Oga-in-5i |
Novel potent O-GlcNAcase (OGA) inhibitor (IC 50 : 46 nM), increasing the level of O-GlcNAcylated protein in cells and displaying suitable pharmacokinetic properties and brain permeability |
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DCC3882 |
Ohinitib |
Novel HSF1 inhibitor for target-based cancer therapy |
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DCC3883 |
Oh-nplh2 |
Novel luciferin analog, enabling both sensitive and highly resolved imaging in vivo |
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DCC3884 |
Oicr766a |
Novel Bax activator, having greatest effect enhancing the pro-apoptotic activity of Bax with EC50 values of ∼0.1 μM and ∼0.9 μM, respectively, inducing cell death by a Bax/Bak-dependent mechanism |
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DCC3885 |
Ojak-989 |
Novel orally bioavailable potent JAK-1 inhibitor |
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DCC3886 |
Okadaic Acid |
Inhibitor of type 1 and type 2A protein phosphatases; Tumor promotor |
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DCC3887 |
Okadaic Acid Potassium Salt |
Inhibitor of type 1 and type 2A protein phosphatases; Tumor promotor |
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DCC3888 |
Okadaic Acid Sodium Salt |
Inhibitor of type 1 and type 2A protein phosphatases; Tumor promotor |
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DCC3889 |
Olanzapine Pamoate |
Dopamine antagonist as an atypical antipsychotic |
|
DCC3890 |
Olanzapine/samidorphan |
Combination of the atypical antipsychotic olanzapine and opioid receptor antagonist samidorphan for treatment of adults with schizophrenia or bipolar I disorder |
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DCC3891 |
Oleanonic Acid |
Natural inhibitor of the phosphorylation of protein kinase C ζ (PKCζ) at Thr410 site, reducing the activation of NF-κB using gain- and loss-of-function approaches in PE-treated cardiomyocytes, ameliorating pressure overload-induced cardiac hypertrophy |
|
DCC3892 |
Oleracein E |
Potent antioxidant and neuroprotectant for treatment of Parkinson's disease, reducing reactive oxygen species (ROS) levels, inhibiting extracellular signal-regulated kinase (ERK) 1/2 phosphorylation, reducing rotenone-induced up-regulation of the proapopt |
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DCC3893 |
Olfr895-agonist-10 |
Novel specific agonist of odorant receptor 895 (Olfr895) |
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DCC3894 |
Olmutinib Hydrochloride |
Novel Bruton's tyrosine kinase inhibitor, suppressing B cell and monocyte activation and ameliorates arthritis in a mouse model |
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DCC3895 |
Olprinone |
Phosphodiesterase III inhibitor, augmenting cerebral blood flow by a direct vasodilator effect on cerebral arteries |
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DCC3896 |
Omdm-188 |
Novel potent DAGL inhibitor, inhibiting collagen-, but not arachidonic acid-induced aggregation and TxA2 synthesis |
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DCC3897 |
On012380 |
Non-ATP-competitive Bcr-Abl inhibitor, potently inhibiting imatinib-resistant Bcr-Abl mutants such as T315I |
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DCC3898 |
Oncrasin-72 |
Potent analogue of oncrasin-1 with antitumor activity mediated by JNK activation and STAT3 inhibition |
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DCC3899 |
Ono12380 |
Novel non-ATP-competitive inhibitor of BCR-ABL, overriding imatinib resistance |
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DCC3900 |
Ono-2910 |
Novel enhancer of Schwann cell differentiation for treatment of peripheral nerve disorder |
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DCC3901 |
Ono-3307 |
Protease inhibitor |
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DCC3902 |
Ono-4007 |
Lipid A analog, inducing Th1-type immune response in tumor eradication and restoring nitric oxide production by peritoneal macrophages |
|
DCC3903 |
Ono-4310321 |
Potent, orally available dual CysLT1 and CysLT2 receptor antagonist |
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DCC3904 |
Ono-ae1-259 |
Highly selective agonist of prostaglandin E2 receptor (EP2) |
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DCC3905 |
Ono-ae1-259 Lysine |
Novel selective EP2 receptor agonist, inducing relaxation of smooth muscle |
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DCC3906 |
Ono-ae1-329 |
Novel agonist of the prostaglandin PGE2 receptor EP4 |
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