DC44694 |
Methyl-PEG3-Ald |
Methyl-PEG3-Ald is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44695 |
Propargyl-PEG9-acid |
Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44696 |
Thiol-C9-PEG4-acid |
Thiol-C9-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44697 |
Nonylbenzene-PEG8-OH |
Nonylbenzene-PEG8-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44698 |
Bromo-PEG7-azide |
Bromo-PEG7-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44699 |
t-Butyl acetate-PEG2-CH2COOH |
t-Butyl acetate-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44700 |
Cyclohexane-PEG1-Br |
Cyclohexane-PEG1-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44701 |
BocNH-PEG5-CH2CH2Br |
BocNH-PEG5-CH2CH2Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC44702 |
Tos-PEG3-CH2COOtBu |
Tos-PEG3-CH2COOtBu is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
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DC53120 |
XD2-149
Featured
|
XD2-149 is a napabucasin PROTAC as an effective degrader of the E3 ligase ZFP91 with IC50 of 1 μM and 0.8 μM in pancreatic cancer cell lines, MIA PaCa-2 and BxPC-3, respectively. XD2-149 also reduces the expression of STAT3, pSTAT3, and NQO1 proteins. |
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DC44798 |
ARV-110
Featured
|
ARV-110 is an orally active, specific androgen receptor (AR) PROTAC degrader. ARV-110 promotes ubiquitination and degradation of AR. ARV-110 can be used for the research of prostate cancer. |
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DC44854 |
β-Naphthoflavone-CH2-Br |
β-Naphthoflavone-CH2-Br (β-NF-CH2-Br) is an arylhydrocarbon receptor (AhR) ligand. β-Naphthoflavone-CH2-Br can be used to synthesize the PROTAC β-NF-JQ1.
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DC44855 |
Thalidomide-O-C2-acid |
Thalidomide-O-C2-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44856 |
Thalidomide-O-C3-acid |
Thalidomide-O-C3-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44857 |
Thalidomide-PEG2-NH2 |
Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44858 |
Thalidomide-O-C4-COOH |
Thalidomide-O-C4-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44859 |
Thalidomide-O-C7-NH2 |
Thalidomide-O-C7-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44860 |
Thalidomide-O-C5-acid |
Thalidomide-O-C5-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44861 |
Thalidomide-O-C8-NH2 |
Thalidomide-O-C8-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44862 |
Thalidomide-O-C6-COOH |
Thalidomide-O-C6-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44863 |
Thalidomide-PEG3-NH2 |
Thalidomide-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44864 |
Thalidomide-O-C7-acid |
Thalidomide-O-C7-acid is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44865 |
Thalidomide-Piperazine-Piperidine |
Thalidomide-Piperazine-Piperidine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44866 |
Thalidomide-Piperazine-PEG1-NH2 |
Thalidomide-Piperazine-PEG1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44867 |
Thalidomide-O-C10-NH2 |
Thalidomide-O-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44868 |
Thalidomide-NH-PEG2-COOH |
Thalidomide-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44869 |
Thalidomide-Piperazine-PEG2-NH2 |
Thalidomide-Piperazine-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44870 |
Thalidomide-NH-PEG3-COOH |
Thalidomide-NH-PEG3-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44871 |
Thalidomide-PEG4-Propargyl |
Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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DC44872 |
Thalidomide-PEG5-NH2 |
Thalidomide-PEG5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. |
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