Cat. No. | Product name | CAS No. |
DC8198 |
RTA-408(Omaveloxolone)
Featured
RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-κB. |
1474034-05-3 |
DC5151 |
Rucaparib phosphate (AG-14699, PF-01367338)
Featured
Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM with binding affinity to nine PARP domains. Phase 1/2. |
459868-92-9 |
DC8464 |
Rucaparib(AG-014447)
Featured
Rucaparib inactivates PARP activity in cells with homologous recombination DNA repair pathway mutations at LC50 values ranging from 1.3-5.5 μM. |
283173-50-2 |
DC4230 |
Ruxolitinib (INCB018424)
Featured
Ruxolitinib is a potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5 nM, respectively and is relatively less selective for JAK3 (IC50 = 322 nM). |
941678-49-5 |
DC8309 |
Ruxolitinib Phosphate
Featured
Ruxolitinib Phosphate is a potent and selective Janus kinase (JAK1, IC50 = 5.9 nM and JAK2, IC50 = 5.7 nM) inhibitor. |
1092939-17-7 |
DC7762 |
RX-3117
Featured
RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. |
865838-26-2 |
DC10479 |
RX518(CK-101:EGFR-IN-3)
Featured
RX518(CK-101) is an orally available third-generation and selective inhibitor of certain epidermal growth factor receptor (EGFR) activating mutations. |
1660963-42-7 |
DC7274 |
S1RA
Featured
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
878141-96-9 |
DC9264 |
S1RA hydrochloride
Featured
S1RA(E-52862) is a potent and selective sigma-1 receptor(σ1R, Ki=17 nM), showed good selectivity against σ2R (Ki > 1000 nM). |
1265917-14-3 |
DC11176 |
S44819
S44819 (S 44819, Egis-13529) is a novel potent, competitive, selective antagonist of the α5-GABAAR with Kd of 221 nM, IC50 of 585 nM (α5β2γ2). |
1398496-82-6 |
DC11265 |
S49076 (hydrochloride)
Featured
S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab. |
1265966-31-1 |
DC10071 |
S49076
Featured
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 values below 20 nM. |
1265965-22-7 |
DC12279 |
S55746 hydrochloride (BLC201 (hydrochloride))
S55746 hydrochloride is a potent, orally active and selective BCL-2 inhibitor, with Kis and Kds of 1.3 nM, 520 nM and 3.9 nM, 186 nM for BCL-2 and BCL-XL, respectively. S55746 hydrochloride has antitumor activity. |
1448525-91-4 |
DC12163 |
S55746 (BLC201)
Featured
S55746 (BLC201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BLC201) has antitumor activity with low toxicity[1]. |
1448584-12-0 |
DC10137 |
S63845
Featured
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor; binds human MCL1 with a Kd of 0.19 nM. |
1799633-27-4 |
DC4134 |
Safinamide
Safinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. |
133865-89-1 |
DC8436 |
Salmeterol Xinafoate
Featured
Salmeterol Xinafoate is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. |
94749-08-3 |
DC10444 |
Sapacitabine (CYC682)
Featured
Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity. |
151823-14-2 |
DC7078 |
AZD-8931(Sapitinib)
Featured
Sapitinib(AZD8931) is a reversible, ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 with IC50 of 4 nM, 3 nM and 4 nM respectively. |
848942-61-0 |
DC8627 |
Saquinavir
Featured
Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. |
127779-20-8 |
DC8628 |
Saquinavir Mesylate
Featured
Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. |
149845-06-7 |
DC8224 |
Lifitegrast(SAR 1118)
Featured
SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye. |
1025967-78-5 |