Safinamide|cas 133865-89-1|supplier DC Chemicals

Cas No.:	133865-89-1
Chemical Name:	(S)-2-((4-((3-fluorobenzyl)oxy)benzyl)amino)propanamide
Synonyms:	FCE-28073; FCE 28073; FCE28073; NW 1015; NW1015; NW-1015; PNU 151774E; PNU-151774E; EMD-1195686; EMD1195686; EMD 1195686; Safinamide, Xadago
SMILES:	FC1=CC(COC2=CC=C(CN[C@@H](C)C(N)=O)C=C2)=CC=C1
Formula:	C₁₇H₁₉FN₂O₂
M.Wt:	302.35
Purity:	99%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Safinamide (EMD 1195686; FCE 26743; ) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (EMD 1195686; FCE 26743; ) is voltage-dependent sodium and calcium channel blocker. Safinamide (EMD 1195686; FCE 26743; ) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals.。For the detailed information about the solubility of Safinamide in water, the solubility of Safinamide in DMSO, the solubility of Safinamide in PBS buffer, the animal experiment（test） of Safinamide,the in vivo,in vitro and clinical trial test of Safinamide,the cell experiment（test） of Safinamide,the IC50, EC50 and Affinity of Safinamide, please contact DC Chemicals.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC4134	Safinamide	Safinamide (EMD 1195686; FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A.