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5-HT1A modulator 2 hydrochloride

  Cat. No.:  DC41002  
Chemical Structure
3880-76-0
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Field of application
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT, is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 3880-76-0
Chemical Name: 8-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride
Synonyms: 8-Methoxy-1,2,3,4-tetrahydronaphthalen-2-amine hydrochloride;2-AMINO-8-METHOXY-1,2,3,4-TETRAHYDRONAPHTHALENE HCL;2-Naphthalenamine,1,2,3,4-tetrahydro-8-methoxy-, hydrochloride (1:1);8-methoxy-1,2,3,4-tetrahydro naphthalen-2-amine;8-METHOXY-2-AMINOTETRALIN HYDROCHLORIDE;1,2,3,4-Tetrahydro-8-methoxy-2-naphthalenamine hydrochloride;2-Amino-8-methoxy-1,2,3,4-tetrahydronaphthalenehydrochloride;2-Amino-8-methoxytetralin hydrochloride;8-Methoxy-(2R)-2-amino-1,2,3,4-tetrahydronaphthalene hydrochloride;8-Methoxy-2-amino-1,2,3,4-tetrahydronaphthalene hydrochloride;dl-1,2,3,4-tetrahydro-8-methoxy-2-naphthalenamine hydrochlori;5-HT1A modulator 2 hydrochloride
SMILES: COC1=CC=CC2=C1CC(CC2)N.Cl
Formula: C11H15NO.HCl
M.Wt: 213.70384
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_24015_DC41002_3880-76-0
COA
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Cat. No. Product name Field of application
DC72326 Tabernanthalog Tabernanthalog is a water-soluble, non-hallucinogenic and non-toxic analogue of ibogaine. Tabernanthalog is a 5-HT2A agonist. Tabernanthalog is found to promote structural neural plasticity, reduce alcohol- and heroin-seeking behaviour, and produce antidepressant-like effects in rodents.
DC71747 Aripiprazole monohydrate Aripiprazole (OPC-14597) monohydrate, an atypical antipsychotic, is a potent and high-affinity dopamine D2 receptor partial agonist. Aripiprazole monohydrate is an inverse agonist at 5-HT2B and 5-HT2A receptors and displays partial agonist actions at 5-HT1A, 5-HT2C, D3, and D4 receptors. Aripiprazole monohydrate can be used for the research of schizophrenia and COVID19.
DC71510 Ansofaxine hydrochloride Ansofaxine hydrochloride (LY03005, LPM570065), a triple reuptake inhibitor, inhibits serotonin, dopamine and norepinephrine reuptake with IC50 values of 723, 491 and 763 nM, respectively.
DC71221 CJ033466 CJ033466 is a novel and selective 5-HT4 receptor partial agonist with an EC50 of 9 nM and has gastroprokinetic effect.
DC70441 GR-127935 GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor; displays >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types; blocks porcine carotid vascular response to sumatriptan in vivo; orally bioavailable and centrally active.
DC70176 AGH-107 AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.AGH-107 exhibited high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.
DC49608 RS 67333 hydrochloride RS 67333 hydrochloride is a potent and selective 5-HT4 receptor (5-HT4R) partial agonist with a pKi of 8.7 in guinea-pig striatum. RS 67333 hydrochloride exhibits lower affinities at several other receptors including 5-HT1A, 5-HT1D, 5-HT2A, 5-HT2C, dopamine D1, D2 and muscarinic M1-M3 receptors. RS 67333 hydrochloride has neuroprotective effects, and can be used for Alzheimer's disease research.
DC48644 Zacopride hydrochloride Zacopride hydrochloride is a potent antagonist of 5-HT3 receptor with a Ki of 0.38 nM. Zacopride hydrochloride is also a agonist of 5-HT4 receptor with a Ki of 373 nM. Zacopride hydrochloride has anxiolytic activity. Zacopride hydrochloride has the potential for the research of Schizophrenia.
DC46455 SB 204741 SB 204741 is a selective and high affinity 5-HT2B antagonist with a pKi value of 7.1.
DC45564 F13714 fumarate F13714 fumarate, a selective 5-HT1A receptor biased agonist, shows antidepressant-like properties after a single administration in the mouse model of chronic mild stress.
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