| DC47752 |
142I5
|
142I5 is a potent ML-IAP Lys-covalent inhibitor with an IC50 value of 11 nM. |
| DC47751 |
Lepidozin G
|
Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis. |
| DC47750 |
L-threo-PPMP
|
L-threo-PPMP is a GlcT (UDP-Glc: Ceramide β1,1glucosyltransferase) inhibitor. L-threo-PPMP inhibits glycosphingolipid biosynthesis and induces apoptosis. L-threo-PPMP has anti-cancer activity. |
| DC47749 |
(±)-Norcantharidin
|
(±)-Norcantharidin ((±)-NCTD) is a compound possessing anti-angiogenetic activity with potential use in anti-cancertherapy. (±)-Norcantharidin could prevent tumorigenesis by inhibiting cell proliferation, inducing apoptosis and the cell cycle arrest, and anti-angiogenic effects. |
| DC47232 |
13-Methyltetradecanoic acid
|
13-Methyltetradecanoic acid (13-MTD), a saturated branched-chain fatty acid with potent anticancer effects. 13-Methyltetradecanoic acid induces apoptosis in many types of human cancer cells. |
| DC47136 |
Enterolactone
|
Enterolactone is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Enterolactone has estrogenic properties and anti-breast cancer activity. Enterolactone is a radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis. |
| DC47002 |
Imifoplatin
|
Imifoplatin is a platinum-based agent belonging to the phosphaplatin family. Imifoplatin exhibits antineoplastic activity. |
| DC46823 |
TCS PrP Inhibitor 13
|
TCS PrP Inhibitor 13, an antiprion agent, is a cellular prion protein (PrPC) inhibitor. TCS PrP Inhibitor 13, as a protease-resistant form of prion protein (PrP-res) accumulation inhibitor, shows an IC50 value of 3 nM in both ScN2a and F3 cell lines. TCS PrP Inhibitor 13 induces Schwannoma cells apoptosis. |
| DC46822 |
cis-Clovamide
|
cis-Clovamide, a natural phenolic compound with antioxidant, anti-inflammatory and antiapoptotic activities. |
| DC46503 |
Girinimbine
|
Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities. |
