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AG-270

  Cat. No.:  DC12499   Featured
Chemical Structure
2201056-66-6
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More than 5000 active chemicals with high quality for research!
Field of application
AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC50 of 14 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2201056-66-6
Chemical Name: 3-(cyclohex-1-en-1-yl)-6-(4-methoxyphenyl)-2-phenyl-5-(pyridin-2-ylamino)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Synonyms: AG-270; AG270; AG 270
SMILES: O=C1C(C2=CC=C(OC)C=C2)=C(NC3=NC=CC=C3)NC4=C(C5=CCCCC5)C(C6=CC=CC=C6)=NN14
Formula: C30H27N5O2
M.Wt: 489.2165
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Zenon Konteatis, et al. Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous MTAP Deletion. J Med Chem. 2021 Apr 8. [2]. Marc L Hyer, et al. The MAT2A inhibitor AG-270 combines with both taxanes and
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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