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AMG-Tie2-1

  Cat. No.:  DC8503   Featured
Chemical Structure
870223-96-4
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More than 5000 active chemicals with high quality for research!
Field of application
AMG-Tie2-1 is a highly potent, non-selective inhibitor of Tie-2 (IC50 <1 nM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 870223-96-4
Chemical Name: 4-methyl-3-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxy-N-[3-(trifluoromethyl)phenyl]benzamide
Synonyms: 870223-96-4; AMG-Tie2; AMG-Tie2-1; 4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide; 4-METHYL-3-[[3-[2-(METHYLAMINO)-4-PYRIMIDINYL]-2-PYRIDINYL]OXY]-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE; PubChem22413
SMILES: CNC1N=C(C=CN=1)C2C(=NC=CC=2)OC3C=C(C=CC=3C)C(=O)NC4=CC(=CC=C4)C(F)(F)F
Formula: C25H20F3N5O2
M.Wt: 479.4
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) and VEGF receptor 2 (VEGFR2) with IC50 values of 1 and 3 nM, respectively.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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