| Description: |
Acitazanolast is an active metabolite of tazanolast and anti-allergic drug. In a study, pretreatment with topical instillation of acitazanolast hydrate inhibited the dye leakage significantly. In the histopathological observation, acitazanolast hydrate ophthalmic solution also improved the inflammatory score and reduced the infiltration of inflammatory cells such as neutrophil and eosinophil in conjunctiva markedly. These anti-allergic effects of acitazanolast hydrate ophthalmic solution were equal to those of levocabastine and ketotifen. From these results, it is suggested that acitazanolast hydrate ophthalmic solution is a promising ophthalmic solution For treatment of allergic conjunctivitis. For the detailed information about the solubility of Acitazanolast (WP-871, Zepelin) in water, the solubility of Acitazanolast (WP-871, Zepelin)in DMSO, the solubility of Acitazanolast (WP-871, Zepelin) in PBS buffer, the animal experiment（test） of Acitazanolast (WP-871, Zepelin),the in vivo,in vitro and clinical trial test of Acitazanolast (WP-871, Zepelin),the cell experiment（test） of Acitazanolast (WP-871, Zepelin),the IC50, EC50 and Affinity of Acitazanolast (WP-871, Zepelin), please contact DC Chemicals. |
