Home > Products > Featured products

AdipoRon

  Cat. No.:  DC7049   Featured
Chemical Structure
924416-43-3
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86-021-58447131
Get Quotation Now
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
AdipoRon is a novel small-molecule AdipoR agonist; binds to both AdipoR1(Kd= 1.8 uM) and AdipoR2(Kd=3.1 uM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 924416-43-3
Chemical Name: AdipoRon
Synonyms: AdipoRon;2-(4-Benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;Acetamide, 2-​(4-​benzoylphenoxy)​-​N-​[1-​(phenylmethyl)​-​4-​piperidinyl]​-;SC-396658;2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]-acetamide;AdipoR agonist;AdipoRon hydrochloride;2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamidehydrochloride;2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide hydrochloride;ND7UVH6GKJ;2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide;C27H28N2O3;Acetamide,2-(4-benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]-;2-(4-Benzoylphenoxy)-N-(1-(phenylmethyl)-4-piperidinyl)acetamide;AMPD00101;HMS3653C18;BCP08895;ZLB41643;2197AH;BDBM50059083;s7365;STL507766;AM85966;MCULE;CCG-268984;CCG-268984;CCG-268984;CCG-268984;SY103513;SY103513;SY103513;SY103513;AS-35052;AS-35052;AS-35052;AS-35052;AC-35903;AC-35903;AC-35903;AC-35903;AN-465/43506510;AN-465/43506510;AN-465/43506510;AN-465/43506510;SCHEMBL17938602;SCHEMBL17938602;SCHEMBL17938602;SCHEMBL17938602;EX-A283;EX-A283;EX-A283;EX-A283;AKOS007999700;AKOS007999700;AKOS007999700;AKOS007999700;NCGC00370758-10;NCGC00370758-10;NCGC00370758-10;NCGC00370758-10;FT-0700407;FT-0700407;FT-0700407;FT-0700407;924416-43-3;924416-43-3;924416-43-3;924416-43-3;2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;2-(4-benzoylphenoxy)-N-(1-benzylpiperidin-4-yl)acetamide;SB17384;SB17384;SB17384;MFCD08271060;SB17384;MFCD08271060;MFCD08271060;SW219831-1;MFCD08271060;SW219831-1;EN300-80366;SW219831-1;SW219831-1;EN300-80366;Z32352521;EN300-80366;EN300-80366;Z32352521;CHEMBL3393145;Z32352521;Z32352521;CHEMBL3393145;2-(4-benzoylphenoxy)-N-(1-benzyl-4-piperidinyl)acetamide;CHEMBL3393145;CHEMBL3393145;Acetamide, 2-(4-benzoylphenoxy)-N-(1-(phenylmethyl)-4-piperidinyl)-;2-(4-benzoylphenoxy)-N-(1-benzyl-4-piperidinyl)acetamide;2-(4-benzoylphenoxy)-N-(1-benzyl-4-piperidinyl)acetamide;2-(4-benzoylphenoxy)-N-(1-benzyl-4-piperidinyl)acetamide;UNII-ND7UVH6GKJ;Acetamide, 2-(4-benzoylphenoxy)-N-(1-(phenylmethyl)-4-piperidinyl)-;Acetamide, 2-(4-benzoylphenoxy)-N-(1-(phenylmethyl)-4-piperidinyl)-;Acetamide, 2-(4-benzoylphenoxy)-N-(1-(phenylmethyl)-4-piperidinyl)-;HY-15848;UNII-ND7UVH6GKJ;UNII-ND7UVH6GKJ;UNII-ND7UVH6GKJ;HY-15848;HY-15848;HY-15848
SMILES: O=C(C([H])([H])OC1C([H])=C([H])C(C(C2C([H])=C([H])C([H])=C([H])C=2[H])=O)=C([H])C=1[H])N([H])C1([H])C([H])([H])C([H])([H])N(C([H])([H])C2C([H])=C([H])C([H])=C([H])C=2[H])C([H])([H])C1([H])[H]
Formula: C27H28N2O3
M.Wt: 428.5228
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: AdipoRon is an orally active adiponectin receptor (AdipoR) agonist, binding to AdipoR1 and AdipoR2 with Kds of 1.8 and 3.1 μM, respectively.
In Vivo: AdipoRon is an orally active and specific AdipoR agonist, binds to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM. AdipoRon (50 nM-50 μM) increases AMPK phosphorylation via AdipoR1[1]. AdipoRon (50 μM) dose-dependently attenuates the expression of TNF-α and TGF-β1 in the L02 cells. AdipoRon exhibits significant and dosage-dependent growth suppression on macrophages[2]. AdipoRon treatment significantly improves cardiac functional recovery after reperfusion, and inhibits post-MI apoptosis[3]. AdipoRon exerts vasodilation by mechanisms distinct to adiponectin and induces vasorelaxation without a marked decrease in VSMC [Ca2+]i[4].
In Vitro: AdipoRon is an orally active and specific AdipoR agonist, binds to AdipoR1 and AdipoR2, with Kds of 1.8 and 3.1 μM. AdipoRon (50 nM-50 μM) increases AMPK phosphorylation via AdipoR1[1]. AdipoRon (50 μM) dose-dependently attenuates the expression of TNF-α and TGF-β1 in the L02 cells. AdipoRon exhibits significant and dosage-dependent growth suppression on macrophages[2]. AdipoRon treatment significantly improves cardiac functional recovery after reperfusion, and inhibits post-MI apoptosis[3]. AdipoRon exerts vasodilation by mechanisms distinct to adiponectin and induces vasorelaxation without a marked decrease in VSMC [Ca2+]i[4].
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC70000 Lysyllysyllysine Lysyllysyllysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles.
DC33580 DODMA DODMA, also known as MBN 305A is a a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery
DC33636 DOTAP DOTAP, also known as 1,2-Dioleoyl-3-trimethylammoniumpropane, is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in gene delivery vectors for gene ther
DC46471 RP101988 RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely.
DC45184 Hydrofurimazine Hydrofurimazine is a NanoLuc substrate whose enhanced aqueous solubility allows delivery of higher doses to mice. Hydrofurimazine enables sensitive bioluminescence imaging for either prolonged light production of high sensitivity.
DC37901 PD-173212 PD-173212 is a small molecule N-type calcium channel blocker.
DC37333 N,N-Diethyl-p-toluamide N,N-Diethyl-p-toluamide is a mosquito repellent.
DC37321 AI3-15902 AI3-15902 is a biochemical.
DC37283 Methyl phenylcarbamate Methyl phenylcarbamate is a biochemical.
DC37252 Ampyrone Ampyrone is a metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.
X
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Site Map|Privacy PolicyCopyright © 2018-2020 All Rights Reserved. Technical Support:KuuJia