| DC47541 |
SC13
|
SC13 is a novel mitragynine analog with low-efficacy Mu opioid receptor agonism that displays antinociception with attenuated adverse effects. |
| DC47074 |
Sunobinop
|
Sunobinop (S 117957) is a modulator of the opioid receptor-like orphan receptor (ORL1). |
| DC46495 |
DIPPA hydrochloride
|
DIPPA (hydrochloride) is an irreversible, long-lasting, selective and high affinity κ-opioid receptor antagonist. DIPPA (hydrochloride) can be used for the research of anxiety and antidepressant. |
| DC45826 |
BMS-986121
|
BMS-986121 is a positive allosteric modulator (PAM) of the μ opioid receptor extracted from patent WO2014107344. BMS-986121 is built on a chemical scaffold representing a new chemotype for μ receptor PAMs. |
| DC45572 |
Nociceptin (1-13), amide TFA
|
Nociceptin (1-13), amide TFA is a potent ORL1 receptor (opioid receptor-like 1 receptor, OP4) agonist with a pEC50 of 7.9 for mouse vas deferens and a Ki of 0.75 nM for binding to rat forebrain membranes. |
| DC45524 |
Deltorphin 2 TFA
|
Deltorphin 2 TFA is a selective peptide agonist for the δ opioid receptor. |
| DC44749 |
6'-GNTI dihydrochloride
|
6'-GNTI dihydrochloride, a κ-opioid receptor (KOR) agonist, displays bias toward the activation of G protein-mediated signaling over β-arrestin2 recruitment. 6'-GNTI 6'-GNTI dihydrochloride only activates the Akt pathway in striatal neurons. |
| DC44147 |
UFP-101 TFA
|
UFP-101 TFA is a potent, selective, and competitive antagonist of the NOP receptor, with a pKi of 10.24. UFP-101 TFA displays >3000-fold selectivity over δ, μ and κ opioid receptors. UFP-101 TFA shows antidepressant-like effect. |
| DC42315 |
Cebranopadol ((1α,4α)stereoisomer)
|
Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol. Cebranopadol is a potent agonist activity on ORL-1. |
| DC41867 |
Dynorphin A (1-8)
|
Dynorphin A (1-8) is the predominant opioid peptide identified in placental tissue extracts. Dynorphin A (1-8) is the most likely natural ligand of the kappa receptor. The binding of 3H-Bremazocine to the purified kappa receptor is inhibited by Dynorphin A (1-8) (IC50=303 nM). |
