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Apelin-36

  Cat. No.:  DC26211   Featured
Chemical Structure
230299-95-3
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More than 5000 active chemicals with high quality for research!
Field of application
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Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 230299-95-3
Chemical Name: Apelin-36(rat, mouse)
Synonyms: LEU-VAL-LYS-PRO-ARG-THR-SER-ARG-THR-GLY-PRO-GLY-ALA-TRP-GLN-GLY-GLY-ARG-ARG-LYS-PHE-ARG-ARG-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE;APELIN-36 (RAT, MOUSE);LEU-VAL-LYS-PRO-ARG-THR-SER-ARG-THR-GLY-PRO-GLY-ALA-TRP-GLN-GLY-GLY-ARG-ARG-LYS-PHE-ARG-ARG-GL...;LEU-VAL-LYS-PRO-ARG-THR-SER-ARG-THR-GLY-PRO-GLY-ALA-TRP-GLN-GLY-GLY-ARG-ARG-LYS-PHE-ARG-ARG-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-G;42-77-Apelin,prepro- (mouse);Apelin (mouse);Apelin (Rattus norvegicus);L-Leucyl-L-valyl-L-lysyl-L-prolyl-L-arginyl-L-threonyl-L-seryl-L-arginyl-L-threonylglycyl-L-prolylglycyl-L-alanyl-L-tryptophyl-L-glutaminylglycylglycyl-L-arginyl-L-arginyl-L-lysyl-L-phenylalanyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanine;CID 131954568;APELIN-36, MOUSE, RAT;Leu-Val-Gln-Pro-Arg-Gly-Ser-Arg-Asn-Gly-Pro-Gly-Pro-Trp-Gln-Gly-Gly-Arg-Arg-Lys-Phe-Arg-Arg-Gln-Arg12-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
SMILES: S(C)CCC(C(N1CCCC1C(NC(C(=O)O)CC1C=CC=CC=1)=O)=O)NC(C1CCCN1C(CNC(C(CCCCN)NC(C(CC1=CNC=N1)NC(C(CO)NC(C(CC(C)C)NC(C(CCCNC(=N)N)NC(C1CCCN1C(C(CCCNC(=N)N)NC(C(CCC(N)=O)NC(C(CCCNC(=N)N)NC(C(CCCNC(=N)N)NC(C(CC1C=CC=CC=1)NC(C(CCCCN)NC(C(CCCNC(=N)N)NC(C(CCCNC(=N)N)NC(CNC(CNC(C(CCC(N)=O)NC(C(CC1=CNC2C=CC=CC1=2)NC(C(C)NC(CNC(C1CCCN1C(CNC(C(C(C)O)NC(C(CCCNC(=N)N)NC(C(CO)NC(C(C(C)O)NC(C(CCCNC(=N)N)NC(C1CCCN1C(C(CCCCN)NC(C(C(C)C)NC(C(CC(C)C)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Formula: C185H304N68O43S
M.Wt: 4200.88809299469
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
Description: Apelin-36(rat, mouse) is an endogenous orphan G protein-coupled receptor APJ agonist. Apelin-36(rat, mouse) binds to APJ receptors with an IC50 of 5.4 nM, and potently inhibits cAMP production with an EC50 of 0.52 nM. Apelin-36(rat, mouse) blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ[1][2].
Target: HIV-1 HIV-2
References: [1]. Kawamata Y, et al. Molecular properties of apelin: tissue distribution and receptor binding. Biochim Biophys Acta. 2001;1538(2-3):162-171. [2]. Zou MX, et al. Apelin peptides block the entry of human immunodeficiency virus (HIV). FEBS Lett. 2000;473(1):15-18.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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