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BSJ-04-132

  Cat. No.:  DC40858  
Chemical Structure
2349356-39-2
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More than 5000 active chemicals with high quality for research!
Field of application
BSJ-04-132 is a potent and selective Ribociclib-based CDK4 degrader (PROTAC), with IC50s of 50.6 nM and 30 nM for CDK4/D1 and CDK6/D1, respectively. BSJ-04-132 does not induce CDK6 and IKZF1/3 degradation. BSJ-04-132 has anti-cancer activity.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2349356-39-2
Chemical Name: BSJ-04-132
SMILES: O=C(C1=CC2=CN=C(NC3=NC=C(N4CCN(CCCCNC(COC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)=O)CC4)C=C3)N=C2N1C8CCCC8)N(C)C
Formula: C42H49N11O7
M.Wt: 819.91
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_23871_DC40858_2349356-39-2
COA
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Cat. No. Product name Field of application
DC47585 PROTAC CDK9 ligand-1 PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
DC47584 PROTAC BRD4 ligand-2 PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
DC47372 Bromo-C10-OBn Bromo-C10-OBn is a PROTAC linker that can be used in the synthesis of PROTACs.
DC47371 1-Bromo-6-chlorohexane 1-Bromo-6-chlorohexane is a PROTAC linker can be used in the synthesis of PROTACs.
DC47370 Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC47369 Propargyl-PEG2-CH2COOH Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC47319 Dovitinib-RIBOTAC Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
DC47213 L-Homopropargylglycine hydrochloride L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
DC47212 Boc-bipiperidine-ethynylbenzoic acid Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61.
DC47193 OICR-9429-N-C2-NH2 OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs.
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