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Benznidazole (Synonyms: Benznidazol; Ro 07-1051; Ro 71051)

  Cat. No.:  DC20028   Featured
Chemical Structure
22994-85-0
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More than 5000 active chemicals with high quality for research!
Field of application
Benznidazole (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 22994-85-0
Chemical Name: Benznidazol
Synonyms: 1H-Imidazole-1-acetamide,2-nitro-N-(phenylmethyl)-;Benznidazole;N-Benzyl-2-Nitro-1H-Imidazole-1-Acetamide;N-benzyl-2-(2-nitroimidazol-1-yl)acetamide;Radanil;Benzonidazole;Benznidazol;benzonidazol;Benznidazolum;N-Benzyl-2-nitroimidazole-1-acetamide;N-Benzyl-2-nitroimidazol-1-yl-acetamide;Rochagan;Benznidazolum [INN-Latin];Benznidazol [INN-Spanish];1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)-;Ro 71051;N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide;2-Nitro-N-(phenylmethyl)-1H-imidazole-1-acetamide;Imidazole-1-acetamide, N-be;Ro 07-1051;N-Benzyl-2-nitro-1H-imidazole-1-acetamide;1H-Imidazole-1-acetamide, 2-nitro-N-(phenylmethyl)- [;CS-0013411;CCG-267054;BENZNIDAZOLE (MART.);AKOS024283499;Tox21_112364;N-benzyl-2-(2-nitro-1Himidazol-1-yl)acetamide;MLS001360496;CHEMBL110;J-014932;P01CA02;benznidazole (TN);HMS3369C11;BDBM50089916;Benznidazole [INN];BENZNIDAZOLE [USAN];BENZNIDAZOLE [ORANGE BOOK];NSC-299972;AS-68694;1H-Imidazole-1-acetamide,2-Nitro-n-(phenylmethyl)-;D02489;YC42NRJ1ZD;SR-01000841264;NSC 299972;NSC299972;Benznidazolum (INN-Latin);N-benzyl-2-nitro-1-imidazoleacetamide;SR-01000841264-3;C74184;CCRIS 2200;Rochagan (TN);RO-07-1051;Imidazole-1-acetamide, N-benzyl-2-nitro-;A912716;BENZNIDAZOLUM [WHO-IP LATIN];22994-85-0;BRD-K56156805-001-05-4;Acetamide, N-benzyl-2-(nitroimidazol-1-yl)-;SMR000857153;HMS2233G13;Pyridinium,1-dodecyl-2-[(hydroxyimino)methyl]-,iodide(1:1);NCGC00166238-01;DTXCID7026570;MLS001332409;EN300-1716737;HY-B1548;s3741;N-Benzyl-2-(2-nitro-imidazol-1-yl)-acetamide;CHEBI:133833;UNII-YC42NRJ1ZD;DB11989;Q425300;CAS-22994-85-0;Ragonil;MMV688773;MFCD00243089;Benznidazol (INN-Spanish);MLS001332410;BENZNIDAZOLE;AKOS015916722;SCHEMBL45081;BENZNIDAZOLE [MART.];Ro 07-1051;Ro 71051;SCHEMBL22493029;Tox21_112364_1;NS00068191;NCGC00166238-02;BENZNIDAZOLE [MI];N-Benzyl-2-(2-nitro-imidazol-1-yl)-acetamide (Benznidazole);SR-01000841264-4;BENZNIDAZOLE [WHO-IP];BENZNIDAZOLE [WHO-DD];Z2044771577;DTXSID9046570;Radanil (TN);Benznidazol (Ro 07-1051; Ro 71051);BRN 0551486;Ro-7-1051;N-benzyl-2-(2-nitro-1H-imidazol-5-yl)acetamide;N-Benzyl-2-nitro-1H-imidazole-1-acetamide, 97%;FT-0662547;Benznidazole (USAN/INN);Benznidazole [USAN:INN]
SMILES: O=C(C([H])([H])N1C([H])=C([H])N=C1[N+](=O)[O-])N([H])C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H]
Formula: C12H12N4O3
M.Wt: 260.2487
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: In Vivo Benznidazole (100 mg/kg/day, p.o., 30 days) produces a decrease in electrocardiographic alterations, fewer modifications in the affinity and density of cardiac-receptors, and few isolated areas of fibrosis in the heart, in mice infected with Trypanosoma cruzi Tulahuen strain or SGO-Z12 isolate and treated at 180 days post infection (p.i.) (i.e. chronic phase) with Benznidazole.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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