Brompheniramine hydrogen maleate|cas 980-71-2|DC Chemicals

Cas No.:	980-71-2
Chemical Name:	3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine maleate
Synonyms:	Brompheniramine, Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane
SMILES:	OC(/C=C\C(=O)O)=O.CN(CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1)C
Formula:	C₂₀H₂₃BrN₂O₄
M.Wt:	435.318
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Brompheniramine maleate is a histamine H1 receptors antagonist.Brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis. It is a first-generation antihistamine. Brompheniramine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Based on this knowledge, Arvid Carlsson and his colleagues, working at the Swedish company Astra AB, were able to derive the first marketed selective serotonin reuptake inhibitor, zimelidine, from brompheniramine. Brompheniramine had a long half-life and large volume of distribution in normal adults. It also had a prolonged antihistaminic effect in the skin as evidenced by suppression of the wheal and flare response to histamine and by suppression of pruritus.

MSDS

COA

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2018-0101

Cat. No.	Product name	Field of application
DCAPI1517	Zotepine	Zotepine is a SR-2A and D2DR inhibitor (Ki values are 0.69 and 2.3 nM respectively). Zotepine is also a potent histamine H1 receptor antagonist (IC50 = 8.0 nM).
DCAPI1584	Roxatidine Acetate Hydrochloride	Roxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist used in ulcer treatment. This compound has been found to inhibit platelet function in vitro.
DC9083	Pheniramine Maleate	Pheniramine Maleate ia an antihistamine and vasoconstrictor.
DC9018	Pemirolast potassium	Pemirolast Potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
DC9132	Ketotifen fumarate	Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks.
DC9073	Famotidine	Famotidine is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
DC9109	Doxylamine succinate	Doxylamine is a first generation antihistamine; can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief.
DC9057	Desloratadine	Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies.
DCAPI1536	Cyproheptadine Hydrochloride	Cyproheptadine hydrochloride is a migraine prophylactic and Non-selective SR-2A (5HT2) antagonist. Cyproheptadine hydrochloride is an inhibitor of Histamine H1 Receptor and SR-2C.
DC9002	Cimetidine	Cimetidine is a histamine-2 (H2) receptor antagonist.