Brompheniramine hydrogen maleate

  Cat. No.:  DC9141  
Chemical Structure
980-71-2
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Field of application
Brompheniramine maleate is a histamine H1 receptors antagonist.
Cas No.: 980-71-2
Chemical Name: 3-(4-bromophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine maleate
Synonyms: Brompheniramine, Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane
SMILES: OC(/C=C\C(=O)O)=O.CN(CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1)C
Formula: C20H23BrN2O4
M.Wt: 435.318
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Brompheniramine maleate is a histamine H1 receptors antagonist.Brompheniramine maleate, is an antihistamine drug of the propylamine (alkylamine) class. It is readily available over the counter and is indicated for the treatment of the symptoms of the common cold and allergic rhinitis. It is a first-generation antihistamine. Brompheniramine has antidepressant properties, inhibiting reuptake of the neurotransmitter serotonin. Based on this knowledge, Arvid Carlsson and his colleagues, working at the Swedish company Astra AB, were able to derive the first marketed selective serotonin reuptake inhibitor, zimelidine, from brompheniramine. Brompheniramine had a long half-life and large volume of distribution in normal adults. It also had a prolonged antihistaminic effect in the skin as evidenced by suppression of the wheal and flare response to histamine and by suppression of pruritus.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC9018 Pemirolast potassium Pemirolast Potassium (BMY 26517) is a histamine H1 antagonist and mast cell stabilizer that acts as an antiallergic agent.
DC9132 Ketotifen fumarate Ketotifen (fumarate) is a second-generation noncompetitive H1-antihistamine and mast cell stabilizer, which is used to prevent asthma attacks.
DC9073 Famotidine Famotidine is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
DC9109 Doxylamine succinate Doxylamine is a first generation antihistamine; can be used by itself as a short-term sedative and in combination with other drugs to provide night-time allergy and cold relief.
DC9057 Desloratadine Desloratadine(Sch34117) is a potent antagonist for human histamine H1 receptor used to treat allergies.
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DC9002 Cimetidine Cimetidine is a histamine-2 (H2) receptor antagonist.
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