Cas No.: | 929007-72-7 |
Chemical Name: | Benzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]- |
Synonyms: | Benzamide, 2-[[2-[(3-hydroxyphenyl)amino]-4-pyrimidinyl]amino]-;DB07268;DB-07268 |
SMILES: | O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2 |
Formula: | C17H15N5O2 |
M.Wt: | 321.333302736282 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM. |
In Vitro: | DB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively[1]. |