LMD-A

  Cat. No.:  DC11148  
Chemical Structure
850330-77-7
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More than 5000 active chemicals with high quality for research!
Field of application
LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM.
Cas No.: 850330-77-7
Chemical Name: N-(5-(N-((3R,4R)-1-(L-alanyl)-3-methylpiperidin-4-yl)sulfamoyl)naphthalen-1-yl)-2-methylbenzamide
Synonyms: CCR8 antagonist LMD-A
SMILES: C(NC1=C2C(C(S(N[C@H]3CCN(C(=O)[C@@H](C)N)C[C@@H]3C)(=O)=O)=CC=C2)=CC=C1)(=O)C1=CC=CC=C1C
Formula: C27H32N4O4S
M.Wt: 508.637
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: LMD-A (CCR8 antagonist LMD-A) is a highly potent, small molecule antagonist of chemokine receptor CCR8 with EC50 of 2.5 nM; inhibits 10 nM CCL1-induced activation of CCR8 with EC50 of 12 nM, inhibits 4DE4 cells cell migration induced by 3 nM CCL1 with EC50 of 0.58 nM.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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