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2-APB

  Cat. No.:  DC11502  
Chemical Structure
524-95-8
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More than 5000 active chemicals with high quality for research!
Field of application
A membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blcoker.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 524-95-8
Chemical Name: 2-Aminoethoxydiphenylborane
Synonyms: 2ABP;2-Aminoethoxydiphenylborane
SMILES: B(OCCN)(C1=CC=CC=C1)C1=CC=CC=C1
Formula: C14H16BNO
M.Wt: 225.094
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blcoker; stimulates store-operated calcium (SOC) release at 10 uM, increases STIM-Orai channel conductance and limits ion selectivity.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47323 TRPA1 Antagonist 3 TRPA1 Antagonist 3 is a photoswitchable TRPA1 agonist that enables optical control of the TRPA1 channel.
DC47322 4-(Phenyldiazenyl)benzoic acid 4-(Phenyldiazenyl)benzoic acid is a photosensitive and photoswitchable TRPA1 agonist that can be used as pharmacological tools for study of pain signaling.
DC47246 SB 452533 SB 452533 is a potent and selective TRPV1 antagonist with the pKb of 7.8.
DC46699 9-Phenanthrol 9-Phenanthrol (9-Hydroxyphenanthrene, Phenanthren-9-o, 9-Phenanthrenol) is a selective TRPM4 inhibitor with an IC50 in the range of 0.02 μM, without effects on TRPM5.
DC46466 Dihydrocapsiate Dihydrocapsiate, as a compound of capsinoid family, is an orally active TRPV1 agonist. Dihydrocapsiate can be used for the research of metabolism disease.
DC46465 Capsiate Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1.
DC45871 Methyl kakuol Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM.
DC45849 GSK2332255B GSK2332255B is a potent, selective TRPC3 and TRPC6 antagonist with IC50s of 5 nM and 4 nM for rat TRPC3 and rat TRPC6. GSK2332255B shows ≥100-fold selectivity for TRPC3/6 over other calcium-permeable channels.
DC45289 OptoBI-1 OptoBI-1 is a photochromic TRPC3 agonist, which asts as a photopharmacological tool to control of neuronal firing.
DC45288 AMG2850 AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist.
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