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dBRD9

  Cat. No.:  DC11589   Featured
Chemical Structure
2170679-45-3
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More than 5000 active chemicals with high quality for research!
Field of application
dBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2170679-45-3
Chemical Name: 2-((2,6-dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)acetamide
Synonyms: dBRD 9
SMILES: C(NCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O)(=O)CN(CC1=C(OC)C=C(C2C3C(C(=O)N(C)C=2)=CN=CC=3)C=C1OC)C
Formula: C40H45N7O10
M.Wt: 783.839
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: dBRD9 is a PROTAC that bridge the BRD9 bromodomain and the cereblon E3 ubiquitin ligase complex; exhibits markedly enhanced potency compared to parental ligands (10-100 fold).
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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DC48434 TD-165 TD165(TD 165) is a PROTAC-based cereblon (CRBN) degrader that degrads Cav1.2α with the DC50 of 20.4 nM, comprising a cereblon (CRBN) ligand binding group, a linker and an von Hippel-Landau (VHL) binding group.
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