Cas No.: | 674786-20-0 |
Chemical Name: | 1-(3,4-Dihydro-3,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-2-(5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-yl)ethanone |
SMILES: | C(=O)(C1C=C2C(=CC=1O)OC(C)(C)C(O)C2)CC1C(OC)=C2C(=CC=1)OC(C)(C)C=C2 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Dihydromunduletone is a rotenoid derivative that selectively inhibits GPR56 (IC50=21 uM) and GPR114/ADGRG5, but not GPR110 or Class A GPCRs; maximally inhibits GPR56 at 50 uM, also dramatically inhibits GPR114 7TM–stimulated Gs activity; also inhibit the growth of the zebrafish intersegmental vessels. |