Cas No.: | 464924-27-4 |
Chemical Name: | H-SER-LEU-LEU-LYS-NH2 |
Synonyms: | H-SER-LEU-LEU-LYS-NH2;SLLK, Control Peptide for TSP1 Inhibitor;SLLK;SLLK-NH2;L-Lysine, L-seryl-L-leucyl-L-leucyl-;L-Seryl-L-leucyl-L-leucyl-L-lysine |
Formula: | C21H41N5O6 |
M.Wt: | 459.58 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | In Vivo Akita mice treated with 30 mg/kg LSKL have significantly increased nephrin expression, greater than twofold, compared with renal lysates from either saline controls or SLLK-treated mice.TGF-β1 is significantly lower (0.10±0.01 pg/mL) in the plasma of mice receiving LSKL compared with that in plasma of mice receiving SLLK control peptide at day 42 (0.20±0.02 pg/mL; P=0.0001). MRNA expression is assessed in the suprarenal aortic lysates obtained from mice receiving SLLK and LSKL peptides. |