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CD38 inhibitor 78c

  Cat. No.:  DC20332   Featured
Chemical Structure
1700637-55-3
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More than 5000 active chemicals with high quality for research!
Field of application
CD38 inhibitor 78c is a potent, specific, reversible CD38 inhibitor with Ki of 14.5 nM for recombinant human CD38.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1700637-55-3
Chemical Name: MDK-7553
SMILES: CN1C2=C(C=C(C=C2)C3=CN=CS3)C(=CC1=O)NC4CCC(CC4)OCCOC
Formula: C22H27N3O3S
M.Wt: 413.536
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CD38 inhibitor 78c is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for human and mouse, respectively[1].
In Vivo: CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) significantly elevates NAD levels in liver and muscle[1]. Animal Model: Diet induced obese (DIO) C57Bl6 mice[1] Dosage: 30 mg/kg Administration: Orally once Result: NAD levels were significantly increased at both the 2 and 6 h time points in liver and muscle.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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