Gingerenone A

  Cat. No.:  DC20391   Featured
Chemical Structure
128700-97-0
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More than 5000 active chemicals with high quality for research!
Field of application
Gingerenone A is a Nrf2-Gpx4 activator with anti-breast-cancer properties. Gingerenone A results a delayed G2/M in cancer cells, following oxidative stress and senescence responses. Gingerenone A also alleviates ferroptosis in secondary liver injury (SLI) in dextran sodium sulfate (DSS)-induced colitis mice. Gingerenone A can be isolated from Zingiber officinale.
Cas No.: 128700-97-0
Chemical Name: 4-Hepten-3-one,1,7-bis(4-hydroxy-3-methoxyphenyl)-, (4E)-
Synonyms: 4-Hepten-3-one,1,7-bis(4-hydroxy-3-methoxyphenyl)-, (4E)-;Gingerenone A;(E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-4-en-3-one;(E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-4-hepten-3-one;(E)-gingerenone A;1,7-bis(4-hydroxy-3-methoxyphenyl)-hept-4-en-3-one;AC1NQZ22;C10460;CHEMBL1086746;gingerenone-A;RP07048;SureCN4740686;Y7369;(E)-1,7-Bis(3-methoxy-4-hydroxyphenyl)-4-hepten-3-one
SMILES: O=C(CCC1C=CC(O)=C(OC)C=1)/C=C/CCC1C=CC(O)=C(OC)C=1
Formula: C21H24O5
M.Wt: 356.41226
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells; induces apoptosis in cancer cells and suppresses tumor growth in vivo associated with relative phosphorylation levels of JAK2 and S6K1; suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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