ALE-0540

  Cat. No.:  DC20653   Featured
Chemical Structure
234779-34-1
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More than 5000 active chemicals with high quality for research!
Field of application
ALE-0540 is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively.
Cas No.: 234779-34-1
Chemical Name: 1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-((2-hydroxyethyl)amino)-5-nitro-
Synonyms: 1R1L47BXMJ;1H-Benz(de)isoquinoline-1,3(2H)-dione, 2-((2-hydroxyethyl)amino)-5-nitro-;2-(2-hydroxyethylamino)-5-nitrobenzo[de]isoquinoline-1,3-dione;1,3-dione;Oprea1_821712;ALE0540;ALE 0540;BDBM50111443;Q27252774;2-(2-Hydroxy-ethylamino)-5-nitro-benzo[de]isoquinoline-
SMILES: O=C1C2=CC(=CC3=CC=CC(C(N1NCCO)=O)=C23)[N+](=O)[O-]
Formula: C14H11N3O5
M.Wt: 301.254243135452
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: ALE-0540 is a nerve growth factor (NGF) antagonist that inhibits the binding of NGF to TrkA or both p75 and TrkA with IC50 of 5.88 and 3.72 uM, respectively; produces antiallodynic actions in models of neuropathic pain.PainDiscontinued
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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