PF 6260933 dihydrochloride |CAS 1883548-86-4|DC Chemicals

Cas No.:	1883548-86-4
Chemical Name:	PF-06260933 HCl
Synonyms:	PF 06260933 dihydrochloride;5-(4-Chlorophenyl)-[3,3'-bipyridine]-6,6'-diamine dihydrochloride;BCP28969;PF06260933;5-(4-chlorophenyl)-3,3'-bipyridine-6,6'-diamine dihydrochloride;PF-06260933 HCl
SMILES:	ClC1C=CC(=CC=1)C1C(N)=NC=C(C2C=NC(=CC=2)N)C=1.Cl.Cl
Formula:	C₁₆H₁₅Cl₃N₄
M.Wt:	369.67610001564
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

PF 6260933 is a potent, selective and orally bioavailable MAP4K4 inhibitor with kinase IC50 of 3.7 nM, cell IC50 of 160 nM; possesses excellent kinome selectivity and suitable properties for in vivo pharmacological characterization; significantly improves fasting hyperglycemia (44% reduction in blood glucose, 10 mg/kg, bid); also markedly reduces atherosclerotic lesion area in mice.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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