Cas No.: | 1303420-67-8 |
Chemical Name: | PLX5622 free base |
Synonyms: | PLX 5622,PLX-5622 |
SMILES: | COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2 |
Formula: | C21H19F2N5O |
M.Wt: | 395.41 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals[1]. |