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RUC-4

  Cat. No.:  DC21593   Featured
Chemical Structure
1448313-27-6
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More than 5000 active chemicals with high quality for research!
Field of application
A potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors. .
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1448313-27-6
Chemical Name: 2-amino-N-(5-(5-oxo-7-(piperazin-1-yl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-2-yl)pyridin-3-yl)acetamide
Synonyms: RUC4;RUC 4
SMILES: NCC(NC1C=NC=C(C2SC3=NC(N4CCNCC4)=CC(=O)N3N=2)C=1)=O
Formula: C16H18N8O2S
M.Wt: 386.434
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent, selective, non-RGD-mimetic αIIbβ3 integrin receptor antagonist with IC50 of 45 nM, with no activity on αVβ3 receptors.
References: References 1. Miller LM, et al. J Med Chem. 2017 Apr 27;60(8):3241-3251. 2. Jiang JK, et al. Bioorg Med Chem Lett. 2014 Feb 15;24(4):1148-53. View Related Products by Target Integrin
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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