Cas No.: | 163126-81-6 |
Chemical Name: | Sepin-1 |
Synonyms: | 2,2-dimethyl-5-nitro-2H-benzo[d]imidazole 1,3-dioxide |
SMILES: | [O-][N+]1=C2C(C=C(C=C2)[N+]([O-])=O)=[N+](C1(C)C)[O-] |
Formula: | C9H9N3O4 |
M.Wt: | 223.188 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM; inhibits the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis. |