Ryuvidine(SPS8I-2)|cas 265312-55-8|DC Chemicals

Cas No.:	265312-55-8
Chemical Name:	4,7-Benzothiazoledione, 2-methyl-5-[(4-methylphenyl)amino]-
SMILES:	CC1=CC=C(C=C1)NC2C(=O)C3=C(SC(C)=N3)C(=O)C=2
Formula:	C₁₅H₁₂N₂O₂S
M.Wt:	284.33298
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Ryuvidine is a potent, selective CDK4 inhibitor with IC50 of 6.0 uM, displays >30-fold selectivity over CDK2 (IC50>100 uM); shows potent cytototoxic activity against HL-60, A549, Col 1, HepG2 cancer cell lines with IC50 of 0.3-1.2 ug/mL; also inhibits SETD8 with IC50 of 0.5 uM, efficiently and selectively suppresses cellular H4K20me1 at doses lower than 5 uM.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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