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Danicamtiv (MYK-491)

  Cat. No.:  DC21881   Featured
Chemical Structure
1970972-74-7
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More than 5000 active chemicals with high quality for research!
Field of application
Danicamtiv (MYK-491), an inotropic agent, is a selective allosteric activator of cardiac myosin. Danicamtiv increases cardiac systolic function and preserves mechanical efficiency.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1970972-74-7
Chemical Name: 4-{(1R)-1-[3-(difluoromethyl)-1-methyl-1H-pyrazole-4-sulfonyl]-1-fluoroethyl}-N-(1,2-oxazol-3-yl)piperidine-1-carboxamide
Synonyms: Danicamtiv|MYK491|MYK-491|MYK 491
SMILES: FC(C1CCN(C(NC2=NOC=C2)=O)CC1)(C)S(C3=CN(C)N=C3C(F)F)(=O)=O
Formula: C16H20F3N5O4S
M.Wt: 435.422
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Sarah Fernandes, et al. Abstract 15707: MYK-491, a Novel Small-Molecule Cardiac Myosin Activator Increases Cardiac Systolic Function and Preserves Mechanical Efficiency: Pre-Clinical in vivo and in vitro Evidence. Circulation. 2019;140:A15707 [2]. V
Description: Danicamtiv is a positive inotropic agent.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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