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BI 167107

  Cat. No.:  DC22021   Featured
Chemical Structure
1202235-68-4
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More than 5000 active chemicals with high quality for research!
Field of application
BI 167107 is a highly potent agonist of the β2 adrenergic receptor (β2AR) and β1AR (IC50=3.2 nM) and shows some activity as α1A antagonist (IC50 = 32 nM).
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1202235-68-4
Chemical Name: 5-hydroxy-8-(1-hydroxy-2-((2-methyl-1-(o-tolyl)propan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
Synonyms: BI 167107|BI167107
SMILES: CC(NCC(C1C2OCC(=O)NC=2C(O)=CC=1)O)(C)CC1C=CC=CC=1C
Formula: C21H26N2O4
M.Wt: 370.449
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Rasmussen SG, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 2011 Jan 13;469(7329):175-80.
Description: BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM[1].
Target: Kd: 84 pM (β2AR)[1]
References: [1]. Rasmussen SG, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 2011 Jan 13;469(7329):175-80.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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